Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10690807 | 0.94 | PPARG (0.50) | PPARGFFAR1MAPTPPARAPTPN1 | |
| SCHEMBL10686384 | 0.87 | PPARG (0.52) | PPARGFFAR1MAPTPPARAPTPN1 | |
| SCHEMBL10686353 | 0.83 | ALDH1A1 (0.48) | PPARGFFAR1MAPTPPARAPTPN1 | |
| SCHEMBL10686465 | 0.79 | PPARG (0.50) | PPARGFFAR1MAPTPPARAPTPN1 | |
| SCHEMBL10686442 | 0.78 | ALDH1A1 (0.50) | PPARGFFAR1MAPTPPARAPTPN1 | |
| SCHEMBL10688903 | 0.77 | CA2 (0.45) | PPARGFFAR1PPARACA2 | |
| SCHEMBL10687505 | 0.75 | PPARG (0.45) | PPARGFFAR1MAPTPPARAPTPN1 | |
| SCHEMBL10690190 | 0.74 | PPARG (0.52) | PPARGFFAR1MAPTPPARAPTPN1 | |
| SCHEMBL10691392 | 0.74 | CYP26A1 (0.56) | PPARGFFAR1MAPTPPARAALDH1A1 | |
| SCHEMBL10686431 | 0.74 | PPARG (0.52) | PPARGFFAR1MAPTPPARAPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4738972-A | Hypoglycemic thiazolidinediones | PFIZER INC. (US) | 1988-04-19 | — | — | US | disclosed |