Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10690582 | 0.94 | PPARG (0.48) | PPARGFFAR1MAPTPPARAPTPN1 | |
| SCHEMBL10686384 | 0.89 | PPARG (0.52) | PPARGFFAR1MAPTPPARAPTPN1 | |
| SCHEMBL10688903 | 0.83 | CA2 (0.45) | PPARGFFAR1PPARACA2 | |
| SCHEMBL10686442 | 0.82 | ALDH1A1 (0.50) | PPARGFFAR1MAPTPPARAPTPN1 | |
| SCHEMBL10686353 | 0.78 | ALDH1A1 (0.48) | PPARGFFAR1MAPTPPARAPTPN1 | |
| SCHEMBL10691392 | 0.78 | CYP26A1 (0.56) | PPARGFFAR1MAPTPPARAALDH1A1 | |
| SCHEMBL10690190 | 0.78 | PPARG (0.52) | PPARGFFAR1MAPTPPARAPTPN1 | |
| SCHEMBL10686431 | 0.78 | PPARG (0.52) | PPARGFFAR1MAPTPPARAPTPN1 | |
| Englitazone SCHEMBL37697 | 0.77 | PPARG (0.50) | PPARGFFAR1MAPTPPARAPTPN1 | |
| Englitazone SCHEMBL4727851 | 0.77 | PPARG (0.50) | PPARGFFAR1MAPTPPARAPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4738972-A | Hypoglycemic thiazolidinediones | PFIZER INC. (US) | 1988-04-19 | — | — | US | disclosed |