Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10609185 | 0.84 | PKM (0.47) | PKMTSHRMAPK1MAPTMEN1 | |
| SCHEMBL10688909 | 0.83 | PKM (0.44) | PKMTSHRMAPK1MAPTMEN1 | |
| SCHEMBL6951629 | 0.83 | FGFR4 (0.46) | TSHRMAPTMEN1KMT2ARAB9A | |
| SCHEMBL10688031 | 0.78 | PKM (0.51) | PKMTSHRMAPK1MAPTMEN1 | |
| SCHEMBL10689294 | 0.77 | PKM (0.50) | PKMTSHRMAPK1MAPTMEN1 | |
| SCHEMBL10687444 | 0.75 | PKM (0.48) | PKMMAPK1MAPTMEN1KMT2A | |
| Isopropylamine SCHEMBL10687587 | 0.75 | PKM (0.46) | PKMMAPTKMT2AALDH1A1VCAM1 | |
| SCHEMBL10687409 | 0.74 | PKM (0.47) | PKMMEN1KMT2AALDH1A1POLB | |
| SCHEMBL6483822 | 0.73 | RIPK2 (0.49) | TSHRMAPK1RAB9AHTTLMNA | |
| SCHEMBL10690689 | 0.73 | PTPN1 (0.43) | TSHRMAPK1MAPTRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4772312-A | PRE-AND POSTEMERGENCE | BAYER AKTIENGESELLSCHAFT (DE) | 1988-09-20 | — | — | US | claimed |
| US-4772312-A | PRE-AND POSTEMERGENCE | BAYER AKTIENGESELLSCHAFT (DE) | 1988-09-20 | — | — | US | disclosed |
| EP-0207285-A1 | 5-Amino-1-pyridyl-pyrazoles | BAYER AG (DE) | 1987-01-07 | — | — | EP | disclosed |