Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.38 |
| ▸ | SRC | P12931 | 4/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 4/20 | 0.38 |
| ▸ | FGFR4 | P22455 | 4/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 4/20 | 0.38 |
| ▸ | KDR | P35968 | 4/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | NNMT | P40261 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 2/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10690689 | 0.89 | PTPN1 (0.43) | RIPK2RAB9ALMNASMN1; SMN2TSHR | |
| SCHEMBL6476731 | 0.84 | MAPK1 (0.56) | RIPK2RAB9ALMNASMN1; SMN2TSHR | |
| SCHEMBL6476695 | 0.83 | MAPT (0.51) | RIPK2RAB9ALMNASMN1; SMN2NPC1 | |
| SCHEMBL10687209 | 0.81 | HTT (0.63) | RAB9ASMN1; SMN2TSHRNPC1HTT | |
| SCHEMBL3610078 | 0.79 | RIPK2 (0.55) | RIPK2RAB9ALMNASMN1; SMN2TSHR | |
| SCHEMBL6475335 | 0.77 | RIPK2 (0.52) | RIPK2RAB9ALMNASMN1; SMN2TSHR | |
| SCHEMBL10717398 | 0.77 | LMNA (0.36) | RAB9ALMNANPC1MAPK1HTT | |
| SCHEMBL27681336 | 0.77 | ALKBH1 (0.43) | LMNASMN1; SMN2TSHRMAPK1MALT1 | |
| SCHEMBL1691724 | 0.75 | RIPK2 (0.60) | RIPK2RAB9ALMNASMN1; SMN2TSHR | |
| SCHEMBL15741922 | 0.74 | MALT1 (0.37) | LMNASMN1; SMN2HTTSRCKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050209251-A1 | Substituted pyrazolo-pyrimidine-4-ones | BAYER CROPSCIENCE AG (DE) | 2005-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050209251-A1 | Substituted pyrazolo-pyrimidine-4-ones | P2RX4, DHFR, DDT | RIPK2 3879/4885RAB9A 1742/4885LMNA 3953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.