Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.40 |
| ▸ | SRC | P12931 | 3/20 | 0.40 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.40 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.40 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.40 |
| ▸ | KDR | P35968 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6483822 | 0.89 | RIPK2 (0.49) | FGFR1SRCFGFR2FGFR4FGFR3 | |
| SCHEMBL27681336 | 0.85 | ALKBH1 (0.43) | PTPN1SMN1; SMN2ALDH1A1MAPTMAPK1 | |
| SCHEMBL15167773 | 0.83 | MAPK1 (0.52) | SMN1; SMN2RAB9AKDM4ENPC1ALDH1A1 | |
| SCHEMBL4541462 | 0.83 | SMN1; SMN2 (0.47) | SMN1; SMN2RAB9AKDM4ENPC1ALDH1A1 | |
| SCHEMBL10687209 | 0.81 | HTT (0.63) | SMN1; SMN2RAB9AKDM4ENPC1ALDH1A1 | |
| SCHEMBL10717398 | 0.80 | LMNA (0.36) | SRCKDRRAB9ANPC1MAPK1 | |
| SCHEMBL2293746 | 0.80 | POLB (0.53) | SMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL28764761 | 0.79 | RIPK2 (0.44) | PTPN1FGFR1SRCFGFR2FGFR4 | |
| SCHEMBL27681333 | 0.75 | PTPN1 (0.49) | PTPN1SMN1; SMN2RAB9AKDM4ENPC1 | |
| SCHEMBL10686367 | 0.73 | PKM (0.44) | RAB9AALDH1A1MAPTMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4772312-A | PRE-AND POSTEMERGENCE | BAYER AKTIENGESELLSCHAFT (DE) | 1988-09-20 | — | — | US | disclosed |