Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6891792 | 0.83 | ALDH1A1 (0.62) | CYP1A2TSHRCYP2C19ALDH1A1KDM4E | |
| SCHEMBL9479735 | 0.81 | CYP1A2 (0.74) | CYP1A2TSHRALDH1A1KDM4EMAPT | |
| SCHEMBL3241378 | 0.81 | CYP1A2 (0.49) | CYP1A2TSHRCYP2C19ALDH1A1KDM4E | |
| SCHEMBL29557923 | 0.81 | CYP1A2 (0.49) | CYP1A2TSHRCYP2C19ALDH1A1KDM4E | |
| SCHEMBL7263686 | 0.80 | CYP1A2 (1.00) | CYP1A2TSHRALDH1A1KDM4EMAPT | |
| SCHEMBL475205 | 0.80 | CYP1A2 (0.72) | CYP1A2TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL7263695 | 0.80 | CYP1A2 (1.00) | CYP1A2TSHRALDH1A1KDM4EMAPT | |
| SCHEMBL185471 | 0.80 | CYP1A2 (0.72) | CYP1A2TSHRALDH1A1KDM4EMAPT | |
| SCHEMBL29475159 | 0.80 | CYP1A2 (0.72) | CYP1A2TSHRALDH1A1KDM4EMAPT | |
| SCHEMBL475201 | 0.80 | CYP1A2 (0.72) | CYP1A2TSHRALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4720506-A | Immunomodulating agent | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1988-01-19 | — | — | US | disclosed |
| EP-0094599-B1 | USE OF AMINOPHENYLACETIC ACID DERIVATIVES FOR THE MANUFACTURE OF AN IMMUNOMODULATING MEDICAL PREPARATION | MITSUBISHI KASEI CORPORATION (JP) | 1987-04-01 | — | — | EP | disclosed |
| EP-0052296-B1 | GLUTAMINE DERIVATIVES USABLE FOR CURING IMMUNE DISEASES, METHODS FOR THEIR PREPARATION AND COMPOSITIONS COMPRISING SAID DERIVATIVES | MITSUBISHI KASEI CORPORATION (JP) | 1984-06-27 | — | — | EP | disclosed |
| US-4439448-A | IMMUNOMODULATING ACTIVITY | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) | 1984-03-27 | — | — | US | disclosed |
| EP-0094599-A1 | Use of aminophenylacetic acid derivatives for the manufacture of an immunomodulating medical preparation | MITSUBISHI KASEI CORPORATION (JP) | 1983-11-23 | — | — | EP | disclosed |
| EP-0052296-A1 | Glutamine derivatives usable for curing immune diseases, methods for their preparation and compositions comprising said derivatives | MITSUBISHI KASEI CORPORATION (JP) | 1982-05-26 | — | — | EP | disclosed |