Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29557923 | 1.00 | CYP1A2 (0.49) | CYP1A2TSHRALDH1A1GPR35CYP3A4 | |
| SCHEMBL6886522 | 0.83 | CYP1A2 (0.46) | CYP1A2TSHRALDH1A1GPR35CYP3A4 | |
| SCHEMBL11461676 | 0.82 | CYP1A2 (0.54) | CYP1A2TSHRALDH1A1GPR35CYP3A4 | |
| SCHEMBL30331074 | 0.82 | CYP1A2 (0.54) | CYP1A2TSHRALDH1A1GPR35CYP3A4 | |
| SCHEMBL10686702 | 0.81 | CYP1A2 (0.67) | CYP1A2TSHRALDH1A1KDM4EMEN1 | |
| SCHEMBL12232402 | 0.81 | CYP1A2 (0.53) | CYP1A2TSHRALDH1A1GPR35CYP3A4 | |
| SCHEMBL7153686 | 0.81 | CYP1A2 (0.53) | CYP1A2TSHRALDH1A1GPR35CYP3A4 | |
| SCHEMBL31145677 | 0.81 | CYP1A2 (0.53) | CYP1A2TSHRALDH1A1GPR35CYP3A4 | |
| SCHEMBL267829 | 0.81 | CYP1A2 (0.53) | CYP1A2TSHRALDH1A1GPR35CYP3A4 | |
| SCHEMBL14599491 | 0.81 | CYP1A2 (0.53) | CYP1A2TSHRALDH1A1GPR35CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114315796-B | Compounds used as HPK1 kinase inhibitor, preparation method and application thereof | 中国药科大学 | 2024-03-26 | — | — | CN | disclosed |
| CN-114315796-A | Compound used as HPK1 kinase inhibitor and preparation method and application thereof | 中国药科大学 | 2022-04-12 | — | — | CN | disclosed |
| EP-3356447-A1 | INHIBITORS OF MENAQUINONE BIOSYNTHESIS | Memorial Sloan-Kettering Cancer Center (US) | 2018-08-08 | — | — | EP | disclosed |
| WO-2017059411-A9 | INHIBITORS OF MENAQUINONE BIOSYNTHESIS | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2017-08-31 | — | — | WO | disclosed |
| WO-2017059411-A9 | INHIBITORS OF MENAQUINONE BIOSYNTHESIS | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2017-08-31 | — | — | WO | disclosed |
| US-20140031562-A1 | Method for Forming Allylic Alcohols | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOI (US) | 2014-01-30 | — | — | US | disclosed |
| US-20140031562-A1 | Method for Forming Allylic Alcohols | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOI (US) | 2014-01-30 | — | — | US | disclosed |
| US-20140031562-A1 | Method for Forming Allylic Alcohols | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOI (US) | 2014-01-30 | — | — | US | disclosed |
| US-20130053556-A1 | Photocleavable morpholino oligos with integral photolinkers for modulating the activity of any selected gene transcript by exposure to light | GENE TOOLS, LLC (US) | 2013-02-28 | — | — | US | disclosed |
| WO-2010025366-A2 | METHOD FOR FORMING ALLYLIC ALCOHOLS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2010-03-04 | — | — | WO | disclosed |
| WO-2010025366-A2 | METHOD FOR FORMING ALLYLIC ALCOHOLS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2010-03-04 | — | — | WO | disclosed |
| US-6124445-A | PRO DRUGS FOR OLIGONUCLEOTIDES HAVING BIOREVERSIBLE PHOSPHATE BLOCKING GROUPS | ISIS PHARMACEUTICALS, INC. (US) | 2000-09-26 | — | — | US | disclosed |
| US-5955591-A | OLIGONUCLEOTIDES HAVING BIOREVERSIBLE PHOSPHATE BLOCKING GROUPS; USED AS PRODRUGS; ANTISENSE AGENTS | CENTER NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1999-09-21 | — | — | US | disclosed |
| EP-0912592-A1 | PHOSPHOTRIESTER OLIGONUCLEOTIDES, AMIDITES AND METHOD OF PREPARATION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1999-05-06 | — | — | EP | disclosed |
| WO-1997047637-A1 | PHOSPHOTRIESTER OLIGONUCLEOTIDES, AMIDITES AND METHOD OF PREPARATION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (US) | 1997-12-18 | — | — | WO | disclosed |
| US-3944540-A | Precipitation of organic dyes and dye intermediates in the presence of finely divided polytetrafluoroethylene | THE HARSHAW CHEMICAL COMPANY (US) | 1976-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140031562-A1 | Method for Forming Allylic Alcohols | ADH1A, ADH1C, ADH5 | CYP1A2 28/4885TSHR 3767/4885ALDH1A1 21/4885 |
| US-20130053556-A1 | Photocleavable morpholino oligos with integral photolinkers for modulating the activity of any selected gene transcript by exposure to light | MITF, RTCB, UPF1 | CYP1A2 2735/4885TSHR 3151/4885ALDH1A1 2417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.