SCHEMBL10686808

SCHEMBL10686808

O=C(Oc1cccc(O)c1O)c1ccccc1O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 7/20 0.71
HPGD P15428 7/20 0.71
ALDH1A1 P00352 6/20 0.71
KDM4E B2RXH2 6/20 0.71
ALOX15 P16050 3/20 0.61
KMT2A Q03164 4/20 0.60
GAA P10253 2/20 0.60
POLB P06746 1/20 0.60
ESR1 P03372 5/20 0.55
ESR2 Q92731 5/20 0.55
MEN1 O00255 2/20 0.55
LMNA P02545 3/20 0.55
TSHR P16473 2/20 0.55
TDP1 Q9NUW8 2/20 0.50
SERPINE1 P05121 1/20 0.50
MAPT P10636 3/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
JAK2 O60674 1/20 0.49
USP2 O75604 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3635482 0.88 HPGD (0.76) HSD17B10HPGDALDH1A1KDM4EALOX15
SCHEMBL10786871 0.87 KMT2A (0.68) HSD17B10HPGDALDH1A1KDM4EALOX15
SCHEMBL22353317 0.84 HSD17B10 (0.56) HSD17B10HPGDALDH1A1KDM4EALOX15
Salsalate SCHEMBL15562 0.83 HSD17B10 (1.00) HSD17B10HPGDALDH1A1KDM4EALOX15
Salsalate SCHEMBL29362887 0.83 HSD17B10 (1.00) HSD17B10HPGDALDH1A1KDM4EALOX15
SCHEMBL7038760 0.83 HSD17B10 (0.74) HSD17B10HPGDALDH1A1KDM4EALOX15
Salsalate SCHEMBL2025628 0.83 HSD17B10 (1.00) HSD17B10HPGDALDH1A1KDM4EALOX15
SCHEMBL31072383 0.82 HSD17B10 (0.63) HSD17B10HPGDALDH1A1KDM4EALOX15
SCHEMBL25135 0.82 KMT2A (0.77) HSD17B10HPGDALDH1A1KDM4EALOX15
SCHEMBL29392731 0.82 KMT2A (0.77) HSD17B10HPGDALDH1A1KDM4EALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0253534-A2 Silver halide photographic paper improved in remaining curl KONICA CORPORATION (JP) 1988-01-20 EP disclosed