Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | HTR5A | P47898 | 3/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 3/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | PDE1A | P54750 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10681792 | 0.89 | SLC6A4 (0.41) | SLC6A4HTR5AABCB1ABCG2MAOA | |
| SCHEMBL10683959 | 0.82 | SLC6A4 (0.41) | SLC6A4HTR5AABCB1ABCG2MAOA | |
| SCHEMBL10688814 | 0.80 | SLC6A4 (0.42) | SLC6A4HTR5AABCB1ABCG2MAOA | |
| SCHEMBL10689191 | 0.80 | SLC6A4 (0.46) | SLC6A4HTR5AABCB1ABCG2MAOA | |
| SCHEMBL10684919 | 0.80 | SLC6A4 (0.39) | SLC6A4HTR5AABCB1ABCG2MAOA | |
| SCHEMBL10686601 | 0.79 | SLC6A4 (0.47) | SLC6A4HTR5AABCB1ABCG2MAOA | |
| SCHEMBL10687983 | 0.76 | ADRA1D (0.47) | SLC6A4ABCB1ABCG2KDM4EALDH1A1 | |
| SCHEMBL10681796 | 0.76 | HTR5A (0.42) | SLC6A4HTR5AABCB1ABCG2HTR2A | |
| SCHEMBL10683964 | 0.75 | HTR5A (0.46) | SLC6A4HTR5AHTR2AHTR2CKDM4E | |
| SCHEMBL10684924 | 0.73 | HTR5A (0.42) | SLC6A4HTR5AKDM4EALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4719208-A | 1,2,3,4,5,6-hexahydroazepino(4,5-B)indole derivatives, their preparation, intermediate compounds, and their application in therapeutics | OMNICHEM SOCIETE ANONYME (BE) | 1988-01-12 | — | — | US | disclosed |