SCHEMBL10690016

SCHEMBL10690016

O=C(O)C(COc1ccccc1)Oc1ccncc1

nearest known ligand 0.68

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PPARG P37231 18/20 0.68
PPARA Q07869 16/20 0.68
LMNA P02545 1/20 0.47
ALDH1A1 P00352 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1538038 0.90 PPARG (0.81) PPARGPPARA
SCHEMBL10844187 0.84 PPARG (0.63) PPARGPPARAALDH1A1
SCHEMBL11302898 0.81 PPARG (0.68) PPARGPPARA
SCHEMBL1967961 0.80 PPARG (0.58) PPARGPPARALMNAALDH1A1
SCHEMBL9482947 0.79 PPARG (0.53) PPARGPPARALMNAALDH1A1
SCHEMBL9173968 0.79 PPARG (0.53) PPARGPPARAALDH1A1
SCHEMBL11019359 0.77 PPARG (0.62) PPARGPPARALMNA
SCHEMBL17132275 0.76 LMNA (0.48) LMNA
SCHEMBL7553627 0.76 GPR132 (0.57) PPARGPPARA
SCHEMBL4651822 0.75 PPARG (0.59) PPARGPPARALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4753673-A GRASSY WEEDS THE DOW CHEMICAL COMPANY (US) 1988-06-28 US disclosed
US-4628099-A INTERMEDIATES FOR HERBICIDES THE DOW CHEMICAL COMPANY (US) 1986-12-09 US disclosed
US-4551170-A Herbicidal trifluoromethyl pyridinyloxyphenoxy and pyridinylthiophenoxy propanols and derivatives thereof THE DOW CHEMICAL COMPANY (US) 1985-11-05 US disclosed
US-4523017-A REACTING CHLORIDE SUBSTITUTED PYRIDINE COMPOUND WITH SUBSTITUTED PHENOL COMPOUND THE DOW CHEMICAL COMPANY (US) 1985-06-11 US disclosed
US-4491468-A Herbicidal trifluoromethyl pyridinyloxyphenoxy and pyridinylthiophenoxy propanenitriles and derivatives thereof THE DOW CHEMICAL COMPANY (US) 1985-01-01 US disclosed
US-4479001-A Trifluoromethyl pyridinylthiophenoxy propanoic acids and propanols and derivatives thereof THE DOW CHEMICAL COMPANY (US) 1984-10-23 US disclosed
US-4325729-A Herbicidal and plant growth regulating pyridyloxy-phenoxy-propionic acid derivatives CIBA-GEIGY CORPORATION (US) 1982-04-20 US disclosed