SCHEMBL11019359

SCHEMBL11019359

NC(=O)C(COc1ccccc1)Oc1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PPARG P37231 8/20 0.62
PPARA Q07869 8/20 0.62
LMNA P02545 1/20 0.47
MTNR1A P48039 3/20 0.46
MTNR1B P49286 3/20 0.46
PARP10 Q53GL7 1/20 0.46
SCN4A P35499 2/20 0.46
ALOX15 P16050 1/20 0.46
MAOA P21397 1/20 0.43
PTGS1 P23219 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1538038 0.85 PPARG (0.81) PPARGPPARA
SCHEMBL9731105 0.83 PPARG (0.46) PPARGPPARALMNAMTNR1AMTNR1B
SCHEMBL11255778 0.81 MTNR1A (0.50) PPARGPPARALMNAMTNR1AMTNR1B
SCHEMBL11304548 0.81 PPARG (0.43) PPARGPPARAMTNR1AMTNR1B
SCHEMBL1433697 0.80 ALDH1A1 (0.52) PPARGPPARALMNA
SCHEMBL4788224 0.80 PPARG (0.48) PPARGPPARA
SCHEMBL10652176 0.79 PPARG (0.52) PPARGPPARAPARP10
SCHEMBL5272171 0.79 PPARG (0.66) PPARGPPARA
SCHEMBL7890153 0.79 PPARG (0.45) PPARGPPARA
SCHEMBL8614509 0.78 MEN1 (0.62)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0011802-B1 PHENOXY-PHENOXY-PROPIONIC ACID AMIDES, PROCESSES FOR THEIR PREPARATION, HERBICIDAL COMPOSITIONS CONTAINING THEM AND THEIR USE IN CONTROLLING THE GROWTH OF WEEDS HOECHST AKTIENGESELLSCHAFT (DE) 1982-09-15 EP claimed
EP-0011802-A1 Phenoxy-phenoxy-propionic acid amides, processes for their preparation, herbicidal compositions containing them and their use in controlling the growth of weeds HOECHST AKTIENGESELLSCHAFT (DE) 1980-06-11 EP claimed
US-4536599-A HYDROLYZING THE NITRILE DERIVATIVE TO THE AMIDE USING AN ORGANIC QUATERNARY AMINE SALT CATALYST; EFFICIENCY SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-08-20 US disclosed
EP-0040896-B1 SYNTHESIS OF AMIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-04-25 EP disclosed
EP-0011802-B1 PHENOXY-PHENOXY-PROPIONIC ACID AMIDES, PROCESSES FOR THEIR PREPARATION, HERBICIDAL COMPOSITIONS CONTAINING THEM AND THEIR USE IN CONTROLLING THE GROWTH OF WEEDS HOECHST AKTIENGESELLSCHAFT (DE) 1982-09-15 EP disclosed
EP-0011802-B1 PHENOXY-PHENOXY-PROPIONIC ACID AMIDES, PROCESSES FOR THEIR PREPARATION, HERBICIDAL COMPOSITIONS CONTAINING THEM AND THEIR USE IN CONTROLLING THE GROWTH OF WEEDS HOECHST AKTIENGESELLSCHAFT (DE) 1982-09-15 EP disclosed
EP-0040896-A2 Synthesis of amides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-12-02 EP disclosed
EP-0011802-A1 Phenoxy-phenoxy-propionic acid amides, processes for their preparation, herbicidal compositions containing them and their use in controlling the growth of weeds HOECHST AKTIENGESELLSCHAFT (DE) 1980-06-11 EP disclosed
EP-0011802-A1 Phenoxy-phenoxy-propionic acid amides, processes for their preparation, herbicidal compositions containing them and their use in controlling the growth of weeds HOECHST AKTIENGESELLSCHAFT (DE) 1980-06-11 EP disclosed
EP-0011802-A1 Phenoxy-phenoxy-propionic acid amides, processes for their preparation, herbicidal compositions containing them and their use in controlling the growth of weeds HOECHST AKTIENGESELLSCHAFT (DE) 1980-06-11 EP disclosed
EP-0008532-A1 Synthesis of amines SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1980-03-05 EP disclosed