Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | PAM | P19021 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KLK7 | P49862 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | KLK6 | Q92876 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694390 | 0.88 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1THRBHPGDPAM | |
| SCHEMBL10692445 | 0.85 | SMN1; SMN2 (0.61) | ALDH1A1L3MBTL1HPGDMAPTRECQL | |
| SCHEMBL10690219 | 0.78 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1HPGDMAPTGAA | |
| SCHEMBL10694410 | 0.78 | KLK7 (0.76) | ALDH1A1L3MBTL1PAMKLK7GAA | |
| SCHEMBL10689558 | 0.77 | SMN1; SMN2 (0.58) | ALDH1A1L3MBTL1HPGDMAPTGAA | |
| SCHEMBL10693834 | 0.77 | SMN1; SMN2 (0.58) | ALDH1A1L3MBTL1HPGDMAPTRECQL | |
| SCHEMBL10693200 | 0.75 | SMN1; SMN2 (0.56) | ALDH1A1L3MBTL1HPGDMAPTMEN1 | |
| SCHEMBL10693670 | 0.75 | EPHX2 (0.56) | — | |
| SCHEMBL10695972 | 0.75 | EPHX2 (0.56) | ALDH1A1L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL10693447 | 0.74 | SMN1; SMN2 (0.54) | ALDH1A1L3MBTL1HPGDMAPTKLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |