Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10690887 | 0.85 | L3MBTL1 (0.64) | ALDH1A1HPGDGAAPOLBRAB9A | |
| SCHEMBL10692720 | 0.84 | GAA (0.57) | ALDH1A1GAAPOLBRAB9AL3MBTL1 | |
| SCHEMBL10692445 | 0.79 | SMN1; SMN2 (0.61) | ALDH1A1HPGDRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL10692512 | 0.79 | HDAC3 (0.63) | ALDH1A1HPGDGAAPOLBHTT | |
| SCHEMBL10690086 | 0.78 | ALDH1A1 (0.56) | ALDH1A1HPGDGAAL3MBTL1MAPT | |
| SCHEMBL10693467 | 0.78 | ABCB1 (0.55) | ALDH1A1GAAPOLBABCB1MEN1 | |
| SCHEMBL8654104 | 0.78 | SOAT1 (0.50) | ALDH1A1HPGDPOLBHDAC1 | |
| SCHEMBL3554353 | 0.77 | SLC16A3 (0.66) | ALDH1A1HPGDSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL15522572 | 0.77 | HDAC1 (0.60) | ALDH1A1HPGDHDAC1MEN1KMT2A | |
| SCHEMBL8286481 | 0.76 | MTNR1A (0.54) | ALDH1A1HPGDPOLBHDAC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |