Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6275913 | 0.78 | BRD4 (0.44) | ALDH1A1TSHRLMNAHPGDBRD4 | |
| SCHEMBL6280031 | 0.77 | DDB1 (0.54) | ALDH1A1LMNAHPGDPKMBRD4 | |
| SCHEMBL7286888 | 0.77 | ALDH1A1 (0.43) | ALDH1A1TSHRTDP1LMNAHPGD | |
| SCHEMBL2003982 | 0.74 | DDB1 (0.59) | ALDH1A1LMNABRD4CREBBPMEN1 | |
| SCHEMBL25575861 | 0.74 | DDB1 (0.66) | ALDH1A1TSHRTDP1LMNAHPGD | |
| SCHEMBL5668502 | 0.73 | DDB1 (0.50) | ALDH1A1TSHRTDP1HPGDBRD4 | |
| SCHEMBL6252884 | 0.72 | BRD4 (0.47) | ALDH1A1TDP1LMNAHPGDBRD4 | |
| SCHEMBL10691415 | 0.70 | DRD2 (0.44) | ALDH1A1TDP1PKMMEN1KMT2A | |
| SCHEMBL5783641 | 0.70 | CREBBP (0.49) | ALDH1A1TSHRBRD4CREBBPMEN1 | |
| SCHEMBL6221253 | 0.70 | CREBBP (0.61) | TSHRBRD4CREBBPMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4778793-A | CONTROLLING CALCIUM CONCENTRATION-CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-10-18 | — | — | US | disclosed |
| EP-0212216-A1 | Dihydroquinolinone derivatives, processes for their preparation, medicaments containing them, the use of these medicaments, and intermediates for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-04 | — | — | EP | disclosed |