Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | UBE2N | P61088 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.47 |
| ▸ | HEXA | P06865 | 3/20 | 0.44 |
| ▸ | HEXB | P07686 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | OGA | O60502 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10690102 | 1.00 | KDM4E (0.47) | KDM4EUBE2NATMCYP1B1HEXA | |
| SCHEMBL27565923 | 0.88 | TBXAS1 (0.45) | NPSR1 | |
| SCHEMBL10857713 | 0.88 | TBXAS1 (0.45) | NPSR1 | |
| SCHEMBL13207604 | 0.83 | CYP1B1 (0.51) | KDM4EUBE2NATMCYP1B1HEXA | |
| SCHEMBL10688300 | 0.80 | HEXA (0.59) | HEXAHEXBMEN1ALOX15KMT2A | |
| SCHEMBL10690041 | 0.80 | HEXA (0.57) | HEXAHEXBNPSR1MEN1ALOX15 | |
| SCHEMBL10685366 | 0.79 | HEXA (0.58) | HEXAHEXBALDH1A1MEN1KMT2A | |
| SCHEMBL10690695 | 0.79 | HEXA (0.58) | HEXAHEXBALDH1A1MEN1KMT2A | |
| SCHEMBL15485550 | 0.74 | CYP1B1 (0.57) | KDM4ECYP1B1HEXAHEXBALDH1A1 | |
| SCHEMBL11801136 | 0.74 | HEXA (0.58) | KDM4ECYP1B1HEXAHEXBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4782064-A | THROMBOXANE SYNTHETASE INHIBITORS | AMERICAN CYANAMID CO. (US) | 1988-11-01 | — | — | US | disclosed |