Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.65 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.55 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | XBP1 | P17861 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.50 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | RXRA | P19793 | 2/20 | 0.49 |
| ▸ | RXRB | P28702 | 2/20 | 0.49 |
| ▸ | RXRG | P48443 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10695989 | 0.84 | ALOX5 (0.66) | ALOX5LTB4RLTB4R2NPC1RAB9A | |
| SCHEMBL10980236 | 0.84 | NPC1 (0.57) | NPC1RAB9ASMN1; SMN2HPGDMAPT | |
| SCHEMBL3950358 | 0.84 | PPARD (0.60) | LTB4RLTB4R2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29394534 | 0.84 | PPARD (0.60) | LTB4RLTB4R2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10832407 | 0.82 | SMN1; SMN2 (0.54) | NPC1RAB9ASMN1; SMN2HPGDMAPT | |
| SCHEMBL10690603 | 0.80 | ALOX5 (0.53) | ALOX5LTB4RLTB4R2NPC1RAB9A | |
| SCHEMBL2755055 | 0.79 | ALOX5 (1.00) | ALOX5LTB4RLTB4R2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL11468082 | 0.79 | LTB4R (0.50) | LTB4RLTB4R2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10915924 | 0.78 | NPC1 (0.49) | LTB4RLTB4R2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11464024 | 0.77 | PDK2 (0.50) | NPC1RAB9ASMN1; SMN2HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792560-A | ANTIALLERGENS; ANTIINFLAMMATORY AGENTS | RORER PHARMACEUTICAL CORPORATION (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0196674-A2 | Hydroxamates as modulators of arachidonic acid metabolic pathways | USV PHARMACEUTICAL CORPORATION (US) | 1986-10-08 | — | — | EP | disclosed |