Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 10/20 | 0.66 |
| ▸ | LTB4R | Q15722 | 6/20 | 0.55 |
| ▸ | LTB4R2 | Q9NPC1 | 6/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9443972 | 0.84 | NPC1 (0.50) | ALOX5NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL10690301 | 0.84 | ALOX5 (0.65) | ALOX5LTB4RLTB4R2NPC1RAB9A | |
| SCHEMBL29394534 | 0.81 | PPARD (0.60) | LTB4RLTB4R2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3950358 | 0.81 | PPARD (0.60) | LTB4RLTB4R2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10695839 | 0.80 | ALOX5 (0.61) | ALOX5LTB4RLTB4R2SMN1; SMN2TP53 | |
| SCHEMBL10693993 | 0.80 | ALOX5 (1.00) | ALOX5LTB4RLTB4R2 | |
| SCHEMBL10695836 | 0.80 | ALOX5 (0.88) | ALOX5LTB4RLTB4R2 | |
| SCHEMBL10692128 | 0.80 | ALOX5 (0.88) | ALOX5LTB4RLTB4R2 | |
| SCHEMBL10980236 | 0.78 | NPC1 (0.57) | NPC1RAB9ASMN1; SMN2HPGDTP53 | |
| SCHEMBL10832407 | 0.76 | SMN1; SMN2 (0.54) | NPC1RAB9ASMN1; SMN2HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0196674-A2 | Hydroxamates as modulators of arachidonic acid metabolic pathways | USV PHARMACEUTICAL CORPORATION (US) | 1986-10-08 | — | — | EP | claimed |
| US-4792560-A | ANTIALLERGENS; ANTIINFLAMMATORY AGENTS | RORER PHARMACEUTICAL CORPORATION (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0196674-A2 | Hydroxamates as modulators of arachidonic acid metabolic pathways | USV PHARMACEUTICAL CORPORATION (US) | 1986-10-08 | — | — | EP | disclosed |