Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10695962 | 0.89 | HTR1B (0.62) | HTR1BCYP1A2CYP2D6KDM4EABCB11 | |
| SCHEMBL10691295 | 0.87 | HTR1B (0.60) | HTR1BCYP1A2CYP2D6KDM4EABCB11 | |
| SCHEMBL10692799 | 0.87 | HTR1B (0.60) | HTR1BCYP1A2CYP2D6KDM4EABCB11 | |
| SCHEMBL10691756 | 0.87 | HTR1B (0.60) | HTR1BCYP1A2CYP2D6KDM4EABCB11 | |
| SCHEMBL23089945 | 0.85 | KCNH2 (0.43) | CYP1A2CYP2D6ABCB11LMNASCN1A | |
| SCHEMBL29371366 | 0.85 | KCNH2 (0.43) | CYP1A2CYP2D6ABCB11LMNASCN1A | |
| SCHEMBL10692715 | 0.85 | L3MBTL1 (0.40) | HTR1BCYP1A2SLC6A4 | |
| SCHEMBL10694848 | 0.84 | HTR1B (0.61) | HTR1BCYP1A2CYP2D6KDM4EABCB11 | |
| SCHEMBL23089966 | 0.84 | KCNA3 (0.42) | CYP1A2CYP2D6ABCB11LMNASCN1A | |
| SCHEMBL23089897 | 0.84 | KCNA3 (0.42) | CYP1A2CYP2D6ABCB11LMNASCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792551-A | 9-anthryloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0132351-A2 | 9-Anthryloxyaminoalkanes and related compounds, processes for their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-01-30 | — | — | EP | disclosed |