SCHEMBL10690364

SCHEMBL10690364

O=C(O)c1cc(Cc2ccccc2)ccc1Oc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HNF4A P41235 1/20 0.59
CFD P00746 1/20 0.56
SRD5A2 P31213 1/20 0.55
FOLH1 Q04609 1/20 0.51
KDM4E B2RXH2 1/20 0.50
POLB P06746 1/20 0.50
PTPN1 P18031 3/20 0.49
PTPN2 P17706 1/20 0.49
PTPN6 P29350 1/20 0.49
KLKB1 P03952 1/20 0.49
CTSB P07858 1/20 0.49
MMP9 P14780 1/20 0.49
DNMT1 P26358 1/20 0.49
DNMT3B Q9UBC3 1/20 0.49
DNMT3L Q9UJW3 1/20 0.49
DNMT3A Q9Y6K1 1/20 0.49
TTR P02766 2/20 0.47
ALDH1A1 P00352 1/20 0.47
CDC25B P30305 1/20 0.47
CASP6 P55212 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1108684 0.85 KDM4E (0.58) HNF4ACFDSRD5A2KDM4EPOLB
SCHEMBL7549968 0.83 CFD (0.55) HNF4ACFDSRD5A2FOLH1KDM4E
SCHEMBL29101125 0.83 HNF4A (0.61) HNF4ACFDFOLH1PTPN1PTPN2
SCHEMBL9158071 0.81 FOLH1 (0.76) HNF4ACFDFOLH1KDM4EPOLB
SCHEMBL14408666 0.81 CFD (0.59) HNF4ACFDFOLH1KDM4EPTPN1
SCHEMBL29353999 0.80 TTR (0.72) HNF4ASRD5A2TTRMPOIDH1
SCHEMBL4794578 0.78 POLB (0.71) SRD5A2KDM4EPOLBTTRALDH1A1
SCHEMBL6098146 0.78 KDM4E (0.48) CFDSRD5A2FOLH1KDM4EPOLB
SCHEMBL4521510 0.78 HNF4A (0.73) HNF4ACFDPTPN1PTPN2PTPN6
SCHEMBL28412115 0.77 CTNNB1 (0.55) SRD5A2KDM4EPOLBTTRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0262810-A2 Sheet recording material containing dye-forming components Fuji Photo Film Co., Ltd. (JP) 1988-04-06 EP disclosed