Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10507144 | 0.86 | ALDH1A1 (0.52) | ALDH1A1TSHRGPR35TDP1HPGD | |
| SCHEMBL249846 | 0.83 | ALDH1A1 (0.68) | ALDH1A1TSHRGPR35TDP1HPGD | |
| SCHEMBL94769 | 0.81 | GPR35 (0.55) | ALDH1A1TSHRGPR35TDP1HPGD | |
| Nitric Acid SCHEMBL9873962 | 0.80 | ALDH1A1 (0.63) | ALDH1A1TSHRGPR35TDP1HPGD | |
| SCHEMBL17141369 | 0.79 | ALDH1A1 (0.49) | ALDH1A1TSHRGPR35TDP1HPGD | |
| SCHEMBL3842170 | 0.79 | TDP1 (0.60) | ALDH1A1TSHRGPR35TDP1MEN1 | |
| Ammonia Solution, Strong SCHEMBL8413128 | 0.79 | ALDH1A1 (0.49) | ALDH1A1TSHRGPR35TDP1HPGD | |
| SCHEMBL994423 | 0.79 | ALDH1A1 (0.49) | ALDH1A1TSHRGPR35TDP1HPGD | |
| SCHEMBL28663049 | 0.79 | ALDH1A1 (0.53) | ALDH1A1TSHRGPR35TDP1HPGD | |
| SCHEMBL11270639 | 0.79 | ALDH1A1 (0.47) | ALDH1A1TSHRGPR35TDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252352-A2 | Highly soluble antibacterially active organic salts of pyridobenzothiazines and their preparation process | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1988-01-13 | — | — | EP | disclosed |