Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16345888 | 0.86 | KDM4E (0.39) | NPSR1KMT2AALDH1A1MAPTHSD17B10 | |
| SCHEMBL10688854 | 0.84 | HSD17B10 (0.43) | KMT2AALDH1A1MAPTHSD17B10TSHR | |
| SCHEMBL10360548 | 0.83 | NPSR1 (0.43) | NPSR1L3MBTL1KMT2AMAPK8MAPK9 | |
| SCHEMBL9748006 | 0.81 | KDM4E (0.42) | L3MBTL1ALDH1A1HSD17B10KDM4ENPC1 | |
| SCHEMBL16604856 | 0.81 | HSD17B10 (0.36) | L3MBTL1ALDH1A1HSD17B10KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL16593684 | 0.80 | KDM4E (0.41) | L3MBTL1ALDH1A1HSD17B10KDM4ENPC1 | |
| SCHEMBL9368410 | 0.80 | L3MBTL1 (0.52) | L3MBTL1KMT2AALDH1A1MAPTTSHR | |
| SCHEMBL9748133 | 0.75 | HSD17B10 (0.32) | L3MBTL1ALDH1A1MAPTHSD17B10KDM4E | |
| SCHEMBL535693 | 0.75 | L3MBTL1 (0.47) | NPSR1L3MBTL1KMT2AMAPK8MAPK9 | |
| SCHEMBL23538248 | 0.72 | NPSR1 (0.46) | NPSR1L3MBTL1MAPK8MAPK9MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4762848-A | IMMUNE SYSTEM STIMULANTS, CYTOSTATIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-09 | — | — | US | disclosed |