Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9749147 | 0.85 | MAPK1 (0.40) | HSD17B10ALDH1A1HPGDMAPK1MAPT | |
| SCHEMBL9852546 | 0.83 | PTGS1 (0.36) | HSD17B10ALDH1A1HPGDMAPK1MAPT | |
| SCHEMBL10690505 | 0.75 | NPSR1 (0.38) | HSD17B10ALDH1A1HPGDL3MBTL1KDM4E | |
| SCHEMBL10872720 | 0.74 | KDM4E (0.36) | HSD17B10ALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL9852497 | 0.72 | KDM4E (0.34) | HSD17B10ALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL9748003 | 0.71 | PTGS1 (0.36) | HSD17B10ALDH1A1HPGDMAPK1MAPT | |
| SCHEMBL16604856 | 0.69 | HSD17B10 (0.36) | HSD17B10ALDH1A1HPGDMAPK1L3MBTL1 | |
| SCHEMBL9748006 | 0.69 | KDM4E (0.42) | HSD17B10ALDH1A1HPGDMAPK1L3MBTL1 | |
| SCHEMBL9749314 | 0.69 | HSD17B10 (0.40) | HSD17B10ALDH1A1HPGDL3MBTL1KDM4E | |
| Hydrochloric Acid SCHEMBL16593684 | 0.68 | KDM4E (0.41) | HSD17B10ALDH1A1HPGDMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194572-B1 | HETEROCYCLIC SULFIDES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-02 | — | — | EP | disclosed |
| EP-0194572-A1 | Heterocyclic sulfides, process for their preparation and Medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-09-17 | — | — | EP | disclosed |