Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL16593684 | 0.98 | KDM4E (0.41) | KDM4EPKMHSD17B10TDP1L3MBTL1 | |
| SCHEMBL16604856 | 0.86 | HSD17B10 (0.36) | KDM4EPKMHSD17B10L3MBTL1ALDH1A1 | |
| SCHEMBL10688331 | 0.82 | CYP1A2 (0.43) | KDM4EPKMHSD17B10L3MBTL1ALDH1A1 | |
| SCHEMBL10690505 | 0.81 | NPSR1 (0.38) | KDM4EHSD17B10L3MBTL1NPC1RAB9A | |
| SCHEMBL16345888 | 0.80 | KDM4E (0.39) | KDM4EPKMHSD17B10NPC1RAB9A | |
| SCHEMBL10685904 | 0.79 | APEX1 (0.43) | KDM4EHSD17B10TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL10360145 | 0.79 | KDM4E (0.48) | KDM4EPKMHSD17B10TDP1L3MBTL1 | |
| SCHEMBL9627261 | 0.78 | KDM4E (0.43) | KDM4ETDP1L3MBTL1NPC1RAB9A | |
| SCHEMBL10692166 | 0.77 | ALDH1A1 (0.44) | KDM4EPKMALDH1A1 | |
| SCHEMBL9852499 | 0.77 | KMT2A (0.40) | KDM4EHSD17B10TDP1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220104496-A1 | PESTICIDALLY ACTIVE BI- OR TRICYCLIC HETEROCYCLES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2022-04-07 | — | — | US | disclosed |
| US-11229208-B2 | Pesticidally active bi- or tricyclic heterocycles with sulfur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2022-01-25 | — | — | US | disclosed |
| US-11229208-B2 | Pesticidally active bi- or tricyclic heterocycles with sulfur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2022-01-25 | — | — | US | disclosed |
| US-10939682-B2 | Pesticidally active bi- or tricyclic heterocycles with sulfur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2021-03-09 | — | — | US | disclosed |
| US-10939682-B2 | Pesticidally active bi- or tricyclic heterocycles with sulfur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2021-03-09 | — | — | US | disclosed |
| EP-3778599-A2 | PESTICIDALLY ACTIVE BI- OR TRICYCLIC HETEROCYCLES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-02-17 | — | — | EP | disclosed |
| EP-3778599-A2 | PESTICIDALLY ACTIVE BI- OR TRICYCLIC HETEROCYCLES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-02-17 | — | — | EP | disclosed |
| EP-3778598-A2 | PESTICIDALLY ACTIVE BI- OR TRICYCLIC HETEROCYCLES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-02-17 | — | — | EP | disclosed |
| EP-3778598-A2 | PESTICIDALLY ACTIVE BI- OR TRICYCLIC HETEROCYCLES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-02-17 | — | — | EP | disclosed |
| US-20210037827-A1 | PESTICIDALLY ACTIVE BI- OR TRICYCLIC HETEROCYCLES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-02-11 | — | — | US | disclosed |
| CN-105431433-A | Pesticidally active bicyclic or tricyclic heterocycles with sulfur-containing substituents | SYNGENTA PARTICIPATIONS AG | 2016-03-23 | — | — | CN | disclosed |
| US-9120792-B2 | Fused heterocyclic compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-09-01 | — | — | US | disclosed |
| US-9120792-B2 | Fused heterocyclic compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-09-01 | — | — | US | disclosed |
| US-20150094329-A1 | FUSED HETEROCYCLIC COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-04-02 | — | — | US | disclosed |
| US-20150094329-A1 | FUSED HETEROCYCLIC COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-04-02 | — | — | US | disclosed |
| WO-2015000715-A1 | PESTICIDALLY ACTIVE BI- OR TRICYCLIC HETEROCYCLES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-01-08 | — | — | WO | disclosed |
| WO-2015000715-A1 | PESTICIDALLY ACTIVE BI- OR TRICYCLIC HETEROCYCLES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-01-08 | — | — | WO | disclosed |
| EP-0194572-B1 | HETEROCYCLIC SULFIDES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-02 | — | — | EP | disclosed |
| US-4762848-A | IMMUNE SYSTEM STIMULANTS, CYTOSTATIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-09 | — | — | US | disclosed |
| EP-0194572-A1 | Heterocyclic sulfides, process for their preparation and Medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-09-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220104496-A1 | PESTICIDALLY ACTIVE BI- OR TRICYCLIC HETEROCYCLES WITH SULFUR CONTAINING SUBSTITUENTS | GSTA1, CYP1B1, DDT | KDM4E 3562/4885PKM 1743/4885HSD17B10 884/4885 |
| US-20210037827-A1 | PESTICIDALLY ACTIVE BI- OR TRICYCLIC HETEROCYCLES WITH SULFUR CONTAINING SUBSTITUENTS | GSTA1, CYP1B1, DDT | KDM4E 3562/4885PKM 1743/4885HSD17B10 884/4885 |
| US-10939682-B2 | Pesticidally active bi- or tricyclic heterocycles with sulfur containing substituents | DDT, TST, SCLY | KDM4E 3403/4885PKM 583/4885HSD17B10 1806/4885 |
| US-11229208-B2 | Pesticidally active bi- or tricyclic heterocycles with sulfur containing substituents | GSTA1, CYP1B1, DDT | KDM4E 3562/4885PKM 1743/4885HSD17B10 884/4885 |
| US-20150094329-A1 | FUSED HETEROCYCLIC COMPOUND | CYC1, H1-0, H1-3 | KDM4E 3132/4885PKM 3331/4885HSD17B10 723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.