Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7778141 | 0.89 | ALDH1A1 (0.45) | KMT2AALDH1A1GAAL3MBTL1SLC16A3 | |
| SCHEMBL10689753 | 0.85 | ALDH1A1 (0.42) | KMT2ALMNASMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL10694450 | 0.85 | ALDH1A1 (0.39) | KMT2ALMNAALDH1A1GAAL3MBTL1 | |
| SCHEMBL10999527 | 0.80 | ALDH1A1 (0.43) | KMT2ASMN1; SMN2ALDH1A1GAAL3MBTL1 | |
| SCHEMBL10693210 | 0.80 | SLC2A1 (0.59) | KMT2ALMNATP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL9657128 | 0.80 | KMT2A (0.44) | KMT2ALMNATP53ATMSMN1; SMN2 | |
| SCHEMBL10689340 | 0.80 | TP53 (0.42) | KMT2ALMNATP53SMN1; SMN2NPSR1 | |
| SCHEMBL7780614 | 0.80 | ALDH1A1 (0.40) | KMT2AALDH1A1GAAL3MBTL1SLC16A3 | |
| SCHEMBL12726665 | 0.79 | ALDH1A1 (0.44) | KMT2ALMNAALDH1A1GAAL3MBTL1 | |
| SCHEMBL10658650 | 0.79 | ALDH1A1 (0.43) | KMT2AATMALDH1A1GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4732991-A | Substituted phthalides | HILTON DAVIS CHEMICAL CO. (US) | 1988-03-22 | — | — | US | disclosed |
| US-4595768-A | 3-(substituted phenyl)phthalides | THE HILTON-DAVIS CHEMICAL CO. (US) | 1986-06-17 | — | — | US | disclosed |