SCHEMBL7778141

SCHEMBL7778141

CN(C)c1ccc(C(c2ccc(N(C)C)cc2)c2ccc(N(C)C)cc2C(=O)O)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.45
KMT2A Q03164 3/20 0.45
GAA P10253 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.44
SLC16A3 O15427 1/20 0.42
MAPT P10636 2/20 0.41
TSHR P16473 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
MAPK1 P28482 1/20 0.41
PHLPP2 Q6ZVD8 1/20 0.41
SLC2A1 P11166 1/20 0.41
MYC P01106 1/20 0.40
KDM4E B2RXH2 2/20 0.40
NPC1 O15118 2/20 0.39
MEN1 O00255 2/20 0.39
POLB P06746 1/20 0.39
HPGD P15428 2/20 0.39
RAB9A P51151 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10999527 0.90 ALDH1A1 (0.43) ALDH1A1KMT2AGAATDP1L3MBTL1
SCHEMBL10693210 0.90 SLC2A1 (0.59) ALDH1A1KMT2ATDP1L3MBTL1MAPT
SCHEMBL10694450 0.90 ALDH1A1 (0.39) ALDH1A1KMT2AGAATDP1L3MBTL1
SCHEMBL10689753 0.90 ALDH1A1 (0.42) ALDH1A1KMT2AGAATDP1L3MBTL1
SCHEMBL7780614 0.90 ALDH1A1 (0.40) ALDH1A1KMT2AGAATDP1L3MBTL1
SCHEMBL12726665 0.89 ALDH1A1 (0.44) ALDH1A1KMT2AGAATDP1L3MBTL1
SCHEMBL7778136 0.89 ALDH1A1 (0.44) ALDH1A1KMT2AGAATDP1L3MBTL1
SCHEMBL10690572 0.89 KMT2A (0.45) ALDH1A1KMT2AGAATDP1L3MBTL1
SCHEMBL7780490 0.89 ALDH1A1 (0.39) ALDH1A1KMT2AGAATDP1L3MBTL1
SCHEMBL8324518 0.89 L3MBTL1 (0.44) ALDH1A1KMT2AGAATDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0373151-B1 PROCESS FOR PRODUCING 2-(4,4'-BIS-(DIMETHYLAMINO)-BENZHYDRYL)-5-DIMETHYL-AMINOBENZOIC ACID YAMADA CHEMICAL CO., LTD. (JP) 1993-09-15 EP claimed
EP-0291600-B1 PROCESS FOR PRODUCING 3,3-BIS-(4-DIMETHYLAMINOPHENYL)-6-DIMETHYLAMINOPHTHALIDE YAMADA CHEMICAL CO., LTD. (JP) 1991-04-03 EP claimed
US-4845245-A Process for producing 3,3-bis-(4-dimethylaminophenyl)-6-dimethylaminophthalide YAMADA CHEMICAL CO., LTD. (JP) 1989-07-04 US claimed
US-4638340-A PROTECTIVE AND DECOLORING INTERMEDIATE LAYERS TO PRODUCE SEPARATE AND DISTINCT COLOR RICOH COMPANY, LTD. (JP) 1987-01-20 US claimed
US-4622565-A FOUR LEUCO DYE LAYERS AND DEVELOPER SUPERIMPOSED ON RECEIVING SHEET; SELECTIVE OVERLAPPING RICOH COMPANY, LTD. (JP) 1986-11-11 US claimed
US-4455435-A Method for the preparation of Leuco Crystal Violet Lactone AMERICAN CYANAMID COMPANY (US) 1984-06-19 US claimed
US-4271075-A COBALT COMPLEX OXIDATION CATALYST HODOGAYA CHEMICAL CO., LTD. (JP) 1981-06-02 US claimed
EP-0008118-B1 PROCESS FOR PREPARING 3,3-BIS-(4-DIMETHYLAMINOPHENYL)-6-DIMETHYLAMINO PHTHALIDE BASF Aktiengesellschaft (DE) 1981-01-07 EP claimed
US-4233223-A Preparation of 3,3-bis-(4-dimethylaminophenyl)-6-dimethylaminophthalide BASF AKTIENGESELLSCHAFT (DE) 1980-11-11 US claimed
US-4076728-A Process for manufacturing crystal violet lactone AMERICAN CYANAMID COMPANY (US) 1978-02-28 US claimed
JP-10298443-A None JP disclosed
JP-55120562-A None JP disclosed
JP-11012264-A None JP disclosed
JP-11012262-A None JP disclosed
JP-63287777-A None JP disclosed
US-4233223-A Preparation of 3,3-bis-(4-dimethylaminophenyl)-6-dimethylaminophthalide BASF AKTIENGESELLSCHAFT (DE) 1980-11-11 US disclosed
JP-S55120562-A IMPROVED METHOD OF PRODUCTION OF 3,3-BIS-(4- DIMETHYLAMINOPHENYL)-6-DIMETHYLAMINOPHTHALIDE HODOGAYA CHEM CO LTD 1980-09-17 JP disclosed
US-4076728-A Process for manufacturing crystal violet lactone AMERICAN CYANAMID COMPANY (US) 1978-02-28 US disclosed
US-4052415-A MANUFACTURE OF LACTONES OF THE TRIPHENYLMETHANE SERIES BASF AKTIENGESELLSCHAFT (DT) 1977-10-04 US disclosed
US-3987062-A Process of preparing 3,3-bis[4-dimethylaminophenyl]6-dimethylaminophthalide IWAKI SEIYAKU CO., LTD. (JA) 1976-10-19 US disclosed