Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | FTO | Q9C0B1 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 6/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10853363 | 0.91 | TDP1 (0.44) | TDP1CYP3A4ALDH1A1HPGDHIF1A | |
| SCHEMBL2905368 | 0.90 | ALDH1A1 (0.68) | TDP1CYP3A4ALDH1A1HPGDHIF1A | |
| SCHEMBL7007875 | 0.80 | TDP1 (0.59) | TDP1CYP3A4ALDH1A1HPGDHIF1A | |
| SCHEMBL10903120 | 0.80 | CYP3A4 (0.60) | TDP1CYP3A4ALDH1A1HPGDHIF1A | |
| SCHEMBL4597988 | 0.80 | ALDH1A1 (0.54) | TDP1CYP3A4ALDH1A1HPGDHIF1A | |
| SCHEMBL311267 | 0.79 | ALDH1A1 (0.79) | TDP1CYP3A4ALDH1A1HPGDHIF1A | |
| SCHEMBL29381342 | 0.79 | ALDH1A1 (0.79) | TDP1CYP3A4ALDH1A1HPGDHIF1A | |
| SCHEMBL29195462 | 0.78 | CYP3A4 (0.52) | TDP1CYP3A4ALDH1A1HPGDHIF1A | |
| SCHEMBL8024125 | 0.78 | ALDH1A1 (0.64) | TDP1CYP3A4ALDH1A1HPGDHIF1A | |
| SCHEMBL4787639 | 0.77 | ALDH1A1 (0.54) | TDP1CYP3A4ALDH1A1HPGDHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4732991-A | Substituted phthalides | HILTON DAVIS CHEMICAL CO. (US) | 1988-03-22 | — | — | US | disclosed |