SCHEMBL4597988

SCHEMBL4597988

Cc1[nH]ccc1C1(c2ccccc2N(C)C)OC(=O)c2cc(N(C)C)ccc21

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.54
TDP1 Q9NUW8 3/20 0.54
CYP3A4 P08684 3/20 0.54
HPGD P15428 2/20 0.54
HIF1A Q16665 2/20 0.54
HSD17B10 Q99714 1/20 0.54
MEN1 O00255 5/20 0.45
KMT2A Q03164 5/20 0.45
MAPT P10636 5/20 0.39
LMNA P02545 5/20 0.39
NPSR1 Q6W5P4 4/20 0.39
POLB P06746 2/20 0.39
ALOX12 P18054 1/20 0.39
GPR55 Q9Y2T6 1/20 0.39
FTO Q9C0B1 5/20 0.37
HTT P42858 2/20 0.37
CYP2C19 P33261 2/20 0.37
RECQL P46063 1/20 0.37
BLM P54132 1/20 0.37
SMAD3 P84022 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2905368 0.88 ALDH1A1 (0.68) ALDH1A1TDP1CYP3A4HPGDHIF1A
SCHEMBL7063811 0.86 ALDH1A1 (0.53) ALDH1A1TDP1CYP3A4HPGDHIF1A
SCHEMBL2039799 0.85 TDP1 (0.72) ALDH1A1TDP1CYP3A4HPGDHIF1A
SCHEMBL10690656 0.80 TDP1 (0.56) ALDH1A1TDP1CYP3A4HPGDHIF1A
SCHEMBL29195462 0.78 CYP3A4 (0.52) ALDH1A1TDP1CYP3A4HPGDHIF1A
SCHEMBL7007875 0.78 TDP1 (0.59) ALDH1A1TDP1CYP3A4HPGDHIF1A
SCHEMBL10903120 0.78 CYP3A4 (0.60) ALDH1A1TDP1CYP3A4HPGDHIF1A
SCHEMBL29381342 0.78 ALDH1A1 (0.79) ALDH1A1TDP1CYP3A4HPGDHIF1A
SCHEMBL311267 0.78 ALDH1A1 (0.79) ALDH1A1TDP1CYP3A4HPGDHIF1A
SCHEMBL4787639 0.76 ALDH1A1 (0.54) ALDH1A1TDP1CYP3A4HPGDHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016198784-A1 THERMOCHROMIC MAKEUP OR TATTOOING MICROCAPSULES AND COMPOSITION INK AND OUT SAS (FR) 2016-12-15 WO disclosed
EP-1877224-A1 ABRASIVE ARTICLE HAVING REACTION ACTIVATED CHROMOPHORE Saint-Gobain Abrasives, Inc. (US) 2008-01-16 EP disclosed
WO-2006110517-A1 ABRASIVE ARTICLE HAVING REACTION ACTIVATED CHROMOPHORE SAINT-GOBAIN ABRASIVES, INC. (US) 2006-10-19 WO disclosed