Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | POLB | P06746 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10690890 | 0.80 | HDAC3 (0.49) | MEN1KMT2APOLBGAAMAPT | |
| SCHEMBL27353720 | 0.79 | LMNA (0.56) | MEN1KMT2AMAPTALDH1A1NPSR1 | |
| SCHEMBL2274138 | 0.74 | ALDH1A1 (0.58) | MEN1KMT2APOLBGAATSHR | |
| SCHEMBL28997262 | 0.72 | MAPT (0.56) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL30226098 | 0.72 | MAPT (0.56) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL22739318 | 0.72 | PTGDR (0.41) | MEN1KMT2APOLBGAAPTGDR | |
| SCHEMBL31519070 | 0.68 | TSHR (0.56) | MEN1KMT2APOLBGAATSHR | |
| SCHEMBL9109237 | 0.68 | CYP3A4 (0.59) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL6391049 | 0.67 | PTGDR (0.60) | MEN1KMT2AGAATSHRPTGDR | |
| SCHEMBL14466455 | 0.67 | ABL1 (0.50) | MEN1KMT2APOLBGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4721797-A | Process for the preparation of N-acyl-N-alkyl-2,6-dialkyl-3-chloroanilines | CIBA-GEIGY CORPORATION (US) | 1988-01-26 | — | — | US | disclosed |
| US-4401833-A | Process for the preparation of 4-chloro-2,6-dialkylanilines | BAYER AKTIENGESELLSCHAFT (DE) | 1983-08-30 | — | — | US | disclosed |