Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 4/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10692302 | 0.84 | ALDH1A1 (0.47) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL4207495 | 0.83 | HDAC3 (0.48) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL7914371 | 0.80 | KDM4E (0.44) | HDAC3HDAC1ALDH1A1HPGDPOLB | |
| SCHEMBL9064516 | 0.80 | ALDH1A1 (0.43) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL10690757 | 0.80 | MEN1 (0.47) | NPC1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL30226017 | 0.79 | HDAC3 (0.60) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL28997259 | 0.79 | RAB9A (0.56) | NAMPTNPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL21442788 | 0.79 | HDAC1 (0.66) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL23060403 | 0.79 | GAA (0.63) | ALDH1A1MEN1KMT2APOLBGAA | |
| SCHEMBL12900197 | 0.79 | TGM2 (0.50) | HDAC3HDAC1ALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4721797-A | Process for the preparation of N-acyl-N-alkyl-2,6-dialkyl-3-chloroanilines | CIBA-GEIGY CORPORATION (US) | 1988-01-26 | — | — | US | disclosed |
| US-4401833-A | Process for the preparation of 4-chloro-2,6-dialkylanilines | BAYER AKTIENGESELLSCHAFT (DE) | 1983-08-30 | — | — | US | disclosed |