Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | EPHB4 | P54760 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24986410 | 0.81 | POLB (0.44) | POLBAOC3CYP3A4ALOX15CYP19A1 | |
| SCHEMBL10430981 | 0.80 | POLB (0.43) | POLBAOC3CYP3A4ALOX15CYP19A1 | |
| SCHEMBL10430644 | 0.80 | POLB (0.48) | POLBAOC3CYP3A4ALOX15CYP19A1 | |
| Hydrochloric Acid SCHEMBL10430668 | 0.79 | POLB (0.42) | POLBAOC3CYP3A4ALOX15CYP19A1 | |
| SCHEMBL1048797 | 0.77 | TAAR1 (0.44) | POLBCYP3A4ALOX15CYP19A1NQO2 | |
| SCHEMBL10430650 | 0.77 | HTR7 (0.45) | POLBCYP3A4ALOX15CYP19A1NQO2 | |
| SCHEMBL2416220 | 0.76 | CYP3A4 (0.61) | POLBCYP3A4ALOX15CYP19A1NQO2 | |
| SCHEMBL11074232 | 0.76 | POLB (0.40) | POLBAOC3CYP3A4ALOX15CYP19A1 | |
| Hydrochloric Acid SCHEMBL10430671 | 0.76 | HTR7 (0.44) | POLBCYP3A4ALOX15CYP19A1NQO2 | |
| SCHEMBL2556563 | 0.75 | TAAR1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4769480-A | Benzylamine derivative | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1988-09-06 | — | — | US | disclosed |
| EP-0214051-A2 | Benzylamine derivative | MITSUBISHI KASEI CORPORATION (JP) | 1987-03-11 | — | — | EP | disclosed |