SCHEMBL2556563

SCHEMBL2556563

COc1c(CC(C)N)ccc2c1OCO2

nearest known ligand 0.66

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.49
SLC6A2 P23975 1/20 0.49
SLC6A4 P31645 1/20 0.49
SLC6A3 Q01959 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5289057 0.82 POLB (0.46) TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL10430981 0.81 POLB (0.43)
Hydrochloric Acid SCHEMBL10430668 0.80 POLB (0.42)
SCHEMBL1067408 0.80 TAAR1 (0.53) TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL24986410 0.79 POLB (0.44)
SCHEMBL23389329 0.78 TAAR1 (0.51) TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL1048797 0.78 TAAR1 (0.44) TAAR1
SCHEMBL29633082 0.78 HTR2A (0.51) TAAR1
SCHEMBL2556707 0.78 HTR2A (0.51) TAAR1
SCHEMBL5308472 0.78 TAAR1 (0.48) TAAR1SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4061359-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH Turtle Bear Holdings, LLC (US) 2022-09-28 EP claimed
WO-2021101926-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH STAMETS PAUL EDWARD (US) 2021-05-27 WO claimed
US-20210145851-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH TURTLE BEAR HOLDINGS, LLC 2021-05-20 US claimed
US-20210069170-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH TURTLE BEAR HOLDINGS, LLC 2021-03-11 US claimed
US-20260108544-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH TURTLE BEAR HOLDINGS LLC (US) 2026-04-23 US disclosed
US-20260108493-A1 COMPOSITIONS COMPRISING A SEROTONERGIC TRYPTAMINE COMPOUND CAAMTECH, INC. (US) 2026-04-23 US disclosed
US-12599578-B2 Compositions comprising enzyme-cleavable prodrugs and controlled release nafamostat and methods of use thereof Ensysce Biosciences Inc. (US) 2026-04-14 US disclosed
EP-4720030-A1 ASYMMETRIC PHENYLALKYLAMINES Alexander Shulgin Research Institute, Inc. (US) 2026-04-08 EP disclosed
US-20260092034-A1 7-AZAINDOLE ANALOGS AND METHODS OF TREATING NEUROLOGICAL DISORDERS USING THE SAME KULEON LLC (US) 2026-04-02 US disclosed
EP-4704806-A1 INJECTABLE PHARMACEUTICAL FORMULATIONS Cybin IRL Limited (IE) 2026-03-11 EP disclosed
US-12570602-B2 Selective serotonin receptor modulators and methods of making and using the same Park City Bio, LLC (US) 2026-03-10 US disclosed
US-12564560-B1 Selective serotonin receptor modulators and methods of making and using the same Park City Bio, LLC (US) 2026-03-03 US disclosed
US-20130059914-A1 Compositions Comprising Enzyme-Cleavable Amphetamine Prodrugs and Inhibitors Thereof SIGNATURE THERAPEUTICS, INC. (US) 2013-03-07 US disclosed
EP-2560486-A1 COMPOSITIONS COMPRISING ENZYME-CLEAVABLE AMPHETAMINE PRODRUGS AND INHIBITORS THEREOF Signature Therapeutics, Inc. (US) 2013-02-27 EP disclosed
WO-2012122412-A2 COMPOSITIONS FOR REDUCING RISK OF ADVERSE EVENTS CAUSED BY DRUG-DRUG INTERACTIONS SIGNATURE THERAPEUTICS, INC. (US) 2012-09-13 WO disclosed
US-20120232066-A1 COMPOSITIONS FOR REDUCING RISK OF ADVERSE EVENTS CAUSED BY DRUG-DRUG INTERACTIONS SIGNATURE THERAPEUTICS, INC. 2012-09-13 US disclosed
WO-2011133348-A1 COMPOSITIONS COMPRISING ENZYME-CLEAVABLE AMPHETAMINE PRODRUGS AND INHIBITORS THEREOF PHARMACOFORE, INC. (US) 2011-10-27 WO disclosed
WO-2011133347-A1 COMPOSITIONS COMPRISING TRYPSIN-CLEAVABLE AMPHETAMINE PRODRUGS AND INHIBITORS THEREOF PHARMACOFORE, INC. (US) 2011-10-27 WO disclosed
WO-2007016190-A2 ANTIPARKINSONIAN ACTION OF PHENYLISOPROPYLAMINES DUKE UNIVERSITY (US) 2007-02-08 WO disclosed
US-20070027208-A1 Antiparkinsonian Action of Phenylisopropylamines NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2007-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092034-A1 7-AZAINDOLE ANALOGS AND METHODS OF TREATING NEUROLOGICAL DISORDERS USING THE SAME HTR2C, HTR7, HTR6 TAAR1 46/4885SLC6A2 56/4885SLC6A4 47/4885
US-20070027208-A1 Antiparkinsonian Action of Phenylisopropylamines PNMT, SNCA, COMT TAAR1 1075/4885SLC6A2 97/4885SLC6A4 178/4885
US-20210145851-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH HTR1B, HTR6, BDNF TAAR1 128/4885SLC6A2 168/4885SLC6A4 62/4885
US-20260108493-A1 COMPOSITIONS COMPRISING A SEROTONERGIC TRYPTAMINE COMPOUND ADRA2C, ADRB3, ADRA2B TAAR1 51/4885SLC6A2 31/4885SLC6A4 28/4885
US-20120232066-A1 COMPOSITIONS FOR REDUCING RISK OF ADVERSE EVENTS CAUSED BY DRUG-DRUG INTERACTIONS CYP2C19, CYP3A5, CYP3A4 TAAR1 1084/4885SLC6A2 494/4885SLC6A4 580/4885
US-12599578-B2 Compositions comprising enzyme-cleavable prodrugs and controlled release nafamostat and methods of use thereof OPRK1, OPRL1, OPRM1 TAAR1 543/4885SLC6A2 1385/4885SLC6A4 1599/4885
US-20210069170-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH HTR1B, HTR6, BDNF TAAR1 128/4885SLC6A2 168/4885SLC6A4 62/4885
US-20130059914-A1 Compositions Comprising Enzyme-Cleavable Amphetamine Prodrugs and Inhibitors Thereof ACHE, COMT, CES2 TAAR1 238/4885SLC6A2 156/4885SLC6A4 352/4885
US-12570602-B2 Selective serotonin receptor modulators and methods of making and using the same HTR1D, HTR1A, HTR4 TAAR1 77/4885SLC6A2 38/4885SLC6A4 19/4885
US-12564560-B1 Selective serotonin receptor modulators and methods of making and using the same HTR5A, HTR1A, HTR1D TAAR1 175/4885SLC6A2 98/4885SLC6A4 21/4885
US-20260108544-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH HTR1B, HTR6, BDNF TAAR1 121/4885SLC6A2 46/4885SLC6A4 26/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.