Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | BAD | Q92934 | 1/20 | 0.34 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24986410 | 0.80 | POLB (0.44) | POLBCYP19A1NQO2CYP3A4ALOX15 | |
| SCHEMBL10430650 | 0.79 | HTR7 (0.45) | POLBCYP19A1NQO2CYP3A4ALOX15 | |
| SCHEMBL10430644 | 0.79 | POLB (0.48) | POLBCYP19A1NQO2CYP3A4ALOX15 | |
| SCHEMBL10430981 | 0.79 | POLB (0.43) | POLBCYP19A1NQO2CYP3A4ALOX15 | |
| Hydrochloric Acid SCHEMBL10430671 | 0.78 | HTR7 (0.44) | POLBCYP19A1NQO2CYP3A4ALOX15 | |
| Hydrochloric Acid SCHEMBL10430668 | 0.78 | POLB (0.42) | POLBCYP19A1NQO2CYP3A4ALOX15 | |
| SCHEMBL231938 | 0.77 | AOC3 (0.41) | CYP19A1NQO2MEN1KMT2AAOC3 | |
| SCHEMBL1048797 | 0.76 | TAAR1 (0.44) | POLBCYP19A1NQO2CYP3A4ALOX15 | |
| SCHEMBL10690900 | 0.76 | POLB (0.41) | POLBCYP19A1NQO2CYP3A4ALOX15 | |
| SCHEMBL16125311 | 0.76 | ALDH1A1 (0.36) | POLBALOX15MEN1KMT2AAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4481207-A | CALCIUM ANTAGONISTS, HYPOTENSIVES | SYNTHELABO (FR) | 1984-11-06 | — | — | US | disclosed |