Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 5/20 | 0.34 |
| ▸ | RAB9A | P51151 | 5/20 | 0.34 |
| ▸ | PDE4A | P27815 | 3/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.34 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.34 |
| ▸ | ALPI | P09923 | 1/20 | 0.34 |
| ▸ | ALPG | P10696 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10693184 | 0.87 | PDE4D (0.36) | PDE4DPOLBMEN1ALDH1A1KMT2A | |
| SCHEMBL10690737 | 0.87 | PDE4D (0.36) | PDE4DPOLBMEN1ALDH1A1KMT2A | |
| SCHEMBL9501827 | 0.82 | POLB (0.40) | PDE4DPOLBMEN1ALDH1A1KMT2A | |
| SCHEMBL9501851 | 0.78 | MPO (0.48) | MEN1ALDH1A1KMT2AALPLNPC1 | |
| SCHEMBL10690439 | 0.78 | NPC1 (0.47) | MEN1ALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL9501844 | 0.77 | PLG (0.43) | MEN1ALDH1A1KMT2AALPLNPC1 | |
| SCHEMBL11107256 | 0.77 | KCNMA1 (0.46) | POLBALPLNPC1RAB9AKCNMA1 | |
| SCHEMBL9501813 | 0.77 | HTT (0.45) | MEN1ALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL9501510 | 0.76 | MPO (0.41) | ALDH1A1ALPLNPC1RAB9AALPI | |
| SCHEMBL11110352 | 0.76 | POLB (0.57) | POLBMEN1ALDH1A1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4764525-A | N-1H-tetrazol-5-ylbenzamides having use as antiallergy and antiinflammatory agents | WARNER-LAMBERT COMPANY (US) | 1988-08-16 | — | — | US | claimed |
| US-4764525-A | N-1H-tetrazol-5-ylbenzamides having use as antiallergy and antiinflammatory agents | WARNER-LAMBERT COMPANY (US) | 1988-08-16 | — | — | US | disclosed |