Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 9/20 | 0.54 |
| ▸ | NPC1 | O15118 | 8/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11111705 | 0.88 | RAB9A (0.57) | RAB9ANPC1SMN1; SMN2TP53GAA | |
| SCHEMBL14511140 | 0.87 | POLB (0.43) | POLBRAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL11562864 | 0.87 | KLKB1 (0.53) | POLBRAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL10879448 | 0.86 | RXFP1 (0.45) | POLBRAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL10879218 | 0.83 | ALDH1A1 (0.47) | RAB9ANPC1SMN1; SMN2TP53GAA | |
| SCHEMBL11193914 | 0.81 | RAB9A (0.48) | POLBRAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL9501827 | 0.80 | POLB (0.40) | POLBRAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL11442680 | 0.80 | MEN1 (0.43) | RAB9ANPC1SMN1; SMN2TP53GAA | |
| SCHEMBL11105633 | 0.79 | ALPL (0.63) | POLBRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11102734 | 0.79 | SMN1; SMN2 (0.45) | POLBRAB9ANPC1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4474792-A | N-Tetrazolyl benzamides and anti-allergic use thereof | RIKER LABORATORIES, INC. (US) | 1984-10-02 | — | — | US | claimed |
| US-4474792-A | N-Tetrazolyl benzamides and anti-allergic use thereof | RIKER LABORATORIES, INC. (US) | 1984-10-02 | — | — | US | disclosed |