SCHEMBL10690946

SCHEMBL10690946

CC(c1ccccc1)N(O)C(=O)Cc1ccc(O)cc1

nearest known ligand 0.71

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 6/20 0.71
CCR5 P51681 1/20 0.49
FNTA P49354 1/20 0.49
FNTB P49356 1/20 0.49
CA2 P00918 1/20 0.44
CAMK2A Q9UQM7 1/20 0.44
NPY5R Q15761 1/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10693843 0.84 ALOX5 (1.00) ALOX5CCR5
SCHEMBL27417085 0.73 ALOX5 (0.53) ALOX5CCR5NPY5RMEN1KMT2A
SCHEMBL27448740 0.73 ALOX5 (0.53) ALOX5CCR5NPY5RMEN1KMT2A
SCHEMBL14210391 0.73 ESR1 (0.50) ALOX5MEN1KMT2A
SCHEMBL14211622 0.73 ESR1 (0.50) ALOX5MEN1KMT2A
SCHEMBL117598 0.73 ALOX5 (0.71) ALOX5
SCHEMBL2334053 0.71 ALOX5 (0.70) ALOX5FNTAFNTBCA2CAMK2A
SCHEMBL9211809 0.71 ALOX5 (0.69) ALOX5
SCHEMBL30624431 0.70 FNTA (0.58) ALOX5FNTAFNTBCA2CAMK2A
SCHEMBL5325376 0.70 CNR1 (0.62) FNTAFNTBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0196674-A2 Hydroxamates as modulators of arachidonic acid metabolic pathways USV PHARMACEUTICAL CORPORATION (US) 1986-10-08 EP claimed
US-4792560-A ANTIALLERGENS; ANTIINFLAMMATORY AGENTS RORER PHARMACEUTICAL CORPORATION (US) 1988-12-20 US disclosed
EP-0196674-A2 Hydroxamates as modulators of arachidonic acid metabolic pathways USV PHARMACEUTICAL CORPORATION (US) 1986-10-08 EP disclosed