SCHEMBL2334053

SCHEMBL2334053

O=C(Cc1ccc(O)cc1)N(O)Cc1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 10/20 0.70
FNTA P49354 1/20 0.59
FNTB P49356 1/20 0.59
BCHE P06276 2/20 0.51
ACHE P22303 2/20 0.51
CA2 P00918 1/20 0.50
CAMK2A Q9UQM7 1/20 0.50
PTGS1 P23219 1/20 0.48
PTGS2 P35354 1/20 0.48
REN P00797 1/20 0.47
TRPM8 Q7Z2W7 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2335482 0.85 ESR1 (0.53) ALOX5FNTAFNTBCA2CAMK2A
SCHEMBL16772742 0.85 ALOX5 (0.52) ALOX5FNTAFNTBBCHEACHE
SCHEMBL10689449 0.83 ALOX5 (1.00) ALOX5PTGS1PTGS2
SCHEMBL10875435 0.81 ALOX5 (0.66) ALOX5PTGS1PTGS2TRPM8
SCHEMBL21085193 0.79 FNTA (0.58) ALOX5FNTAFNTBBCHEACHE
SCHEMBL375755 0.76 FNTA (0.59) FNTAFNTBBCHEACHECA2
SCHEMBL4029483 0.75 FNTA (0.76) FNTAFNTBBCHEACHECA2
Kurasoin A SCHEMBL30799774 0.75 FNTA (1.00) FNTAFNTBBCHEACHECA2
Phenylacetic Acid SCHEMBL29388435 0.75 CA2 (0.86) FNTAFNTBCA2CAMK2APTGS1
SCHEMBL30624431 0.75 FNTA (0.58) ALOX5FNTAFNTBBCHEACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9210928-B2 Plant development control composition SYNGENTA CROP PROTECTION, LLC (US) 2015-12-15 US disclosed
US-20110301028-A1 PLANT DEVELOPMENT CONTROL COMPOSITION SYNGENTA CROP PROTECTION, LLC (US) 2011-12-08 US disclosed
EP-2358197-A2 PLANT DEVELOPMENT CONTROL COMPOSITION Syngenta Participations AG (CH) 2011-08-24 EP disclosed
WO-2010055316-A2 PLANT DEVELOPMENT CONTROL COMPOSITION THE UNIVERSITY OF WARWICK (GB) 2010-05-20 WO disclosed
WO-2010055310-A1 HERBICIDAL COMPOSITIONS THE UNIVERSITY OF WARWICK (GB) 2010-05-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110301028-A1 PLANT DEVELOPMENT CONTROL COMPOSITION MSL1, OXSR1, OSR1 ALOX5 3171/4885FNTA 3845/4885FNTB 3648/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.