Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10705326 | 0.89 | ALDH1A1 (0.40) | ALDH1A1MAPTL3MBTL1NPC1CYP3A4 | |
| SCHEMBL10692792 | 0.76 | TNKS2 (0.38) | ALDH1A1CYP3A4CYP2C9POLBHPGD | |
| SCHEMBL10691474 | 0.71 | TDP1 (0.47) | ALDH1A1L3MBTL1NPC1KMT2A | |
| SCHEMBL205737 | 0.68 | ALDH1A1 (0.50) | ALDH1A1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL8845363 | 0.68 | ALDH1A1 (0.50) | ALDH1A1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL14959157 | 0.68 | ALDH1A1 (0.45) | ALDH1A1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL10692300 | 0.67 | CYP2C19 (0.58) | ALDH1A1MAPTCYP2C9CYP2C19HPGD | |
| SCHEMBL10688054 | 0.65 | CYP1A2 (0.58) | CYP2C9KDM4E | |
| SCHEMBL13291850 | 0.65 | ALDH1A1 (0.47) | ALDH1A1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL813168 | 0.65 | ALDH1A1 (0.47) | ALDH1A1MAPTL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4741846-A | STABILIZERS FOR POLYMERS OR LUBRICANTS | CIBA-GEIGY CORPORATION (US) | 1988-05-03 | — | — | US | disclosed |