Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10705326 | 0.87 | ALDH1A1 (0.40) | TDP1LMNAL3MBTL1ESR1ESR2 | |
| SCHEMBL10702308 | 0.83 | ALDH1A1 (0.45) | TDP1LMNAL3MBTL1KMT2AMAPK1 | |
| SCHEMBL10692792 | 0.79 | TNKS2 (0.38) | TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL2748816 | 0.73 | TDP1 (0.59) | TDP1LMNAL3MBTL1ESR1ESR2 | |
| SCHEMBL9776616 | 0.73 | TDP1 (0.59) | TDP1LMNAL3MBTL1ESR1ESR2 | |
| SCHEMBL6655944 | 0.72 | EGFR (0.46) | LMNANPC1RAB9AALDH1A1 | |
| SCHEMBL2748895 | 0.72 | TDP1 (0.58) | TDP1LMNAL3MBTL1ESR1ESR2 | |
| SCHEMBL10692300 | 0.71 | CYP2C19 (0.58) | TDP1LMNAKMT2AMAPK1TSHR | |
| SCHEMBL10690952 | 0.71 | ALDH1A1 (0.37) | L3MBTL1KMT2ANPC1ALDH1A1 | |
| SCHEMBL137486 | 0.70 | TDP1 (0.83) | TDP1LMNAL3MBTL1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4741846-A | STABILIZERS FOR POLYMERS OR LUBRICANTS | CIBA-GEIGY CORPORATION (US) | 1988-05-03 | — | — | US | disclosed |