Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 5/20 | 0.68 |
| ▸ | MMP9 | P14780 | 5/20 | 0.68 |
| ▸ | MMP8 | P22894 | 5/20 | 0.68 |
| ▸ | MMP13 | P45452 | 5/20 | 0.68 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.56 |
| ▸ | NPBWR1 | P48145 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10689470 | 0.86 | MMP2 (0.70) | MMP2MMP9MMP8MMP13NPBWR1 | |
| SCHEMBL10688373 | 0.85 | MMP2 (0.68) | MMP2MMP9MMP8MMP13SLC2A1 | |
| SCHEMBL10690246 | 0.85 | MMP2 (0.68) | MMP2MMP9MMP8MMP13SLC2A1 | |
| SCHEMBL7461639 | 0.81 | MMP2 (0.64) | MMP2MMP9MMP8MMP13NPBWR1 | |
| SCHEMBL10689852 | 0.81 | MMP2 (0.64) | MMP2MMP9MMP8MMP13SLC2A1 | |
| SCHEMBL10694677 | 0.81 | MMP2 (1.00) | MMP2MMP9MMP8MMP13NPBWR1 | |
| SCHEMBL18890544 | 0.79 | ALDH1A1 (0.49) | MMP2MMP9MMP8MMP13MAPT | |
| SCHEMBL30360160 | 0.77 | MMP2 (0.68) | MMP2MMP9MMP8MMP13NPBWR1 | |
| SCHEMBL2250050 | 0.75 | MMP2 (0.80) | MMP2MMP9MMP8MMP13NPBWR1 | |
| SCHEMBL6826824 | 0.74 | FBP1 (0.42) | MAPTMEN1KMT2ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252028-A1 | Process for preparing nitrofurylbenzimidazoles and pharmaceutical compositions having antimycotic, antibacterial and antitubercular activities containing same | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1988-01-07 | — | — | EP | disclosed |