Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | RELA | Q04206 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL97659 | 0.82 | NPC1 (0.54) | NPC1RAB9ACTSBL3MBTL1ALDH1A1 | |
| SCHEMBL99151 | 0.82 | NPC1 (0.54) | NPC1RAB9ACTSBL3MBTL1ALDH1A1 | |
| SCHEMBL16743643 | 0.77 | HTT (0.54) | NPC1RAB9ACTSBL3MBTL1ALDH1A1 | |
| Bicarbonate SCHEMBL11298239 | 0.77 | KDM4E (0.60) | NPC1RAB9ACTSBL3MBTL1ALDH1A1 | |
| SCHEMBL6637213 | 0.76 | TP53 (0.56) | NPC1RAB9ACTSBL3MBTL1ALDH1A1 | |
| SCHEMBL6640584 | 0.76 | KMT2A (0.60) | NPC1RAB9ACTSBL3MBTL1ALDH1A1 | |
| SCHEMBL8139603 | 0.75 | RAB9A (0.55) | NPC1RAB9ACTSBL3MBTL1ALDH1A1 | |
| SCHEMBL8150025 | 0.75 | CTSB (0.48) | NPC1RAB9ACTSBL3MBTL1ALDH1A1 | |
| SCHEMBL25440116 | 0.75 | TSHR (0.54) | NPC1RAB9ACTSBL3MBTL1ALDH1A1 | |
| SCHEMBL10687383 | 0.74 | APP (0.58) | NPC1RAB9AL3MBTL1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4761173-A | Herbicidal heterocyclic sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-08-02 | — | — | US | disclosed |
| EP-0244269-A2 | Herbicidal heterocyclic sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-11-04 | — | — | EP | disclosed |