Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 3/20 | 0.55 |
| ▸ | IKBKB | O14920 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | F9 | P00740 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5331074 | 0.87 | STING1 (0.56) | STING1IKBKBALDH1A1TSHRKDM4E | |
| SCHEMBL3136911 | 0.76 | ALDH1A1 (0.45) | STING1ALDH1A1KDM4EMAPK1GLA | |
| SCHEMBL9025199 | 0.76 | STING1 (0.54) | STING1ALDH1A1TSHRKDM4EMAPK1 | |
| SCHEMBL10693915 | 0.75 | STING1 (0.42) | STING1ALDH1A1TSHRKDM4EMAPK1 | |
| SCHEMBL23112007 | 0.75 | ALDH1A1 (0.55) | STING1ALDH1A1TSHRKDM4EMAPK1 | |
| SCHEMBL16666142 | 0.73 | GLA (0.52) | ALDH1A1TSHRKDM4EMAPK1GLA | |
| SCHEMBL9024186 | 0.73 | STING1 (0.42) | STING1IKBKBALDH1A1TSHRKDM4E | |
| SCHEMBL23630803 | 0.72 | STING1 (1.00) | STING1ALDH1A1TSHRKDM4EGLA | |
| SCHEMBL3189724 | 0.71 | TSHR (0.53) | TSHRMAPK1GLAL3MBTL1HPGD | |
| SCHEMBL22908996 | 0.71 | ALDH1A1 (0.51) | STING1ALDH1A1TSHRKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253650-A2 | Improvements relating to benzothiophene derivatives | ELI LILLY AND COMPANY (US) | 1988-01-20 | — | — | EP | claimed |
| EP-0253650-A2 | Improvements relating to benzothiophene derivatives | ELI LILLY AND COMPANY (US) | 1988-01-20 | — | — | EP | disclosed |