Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4696202 | 0.93 | MAPK1 (0.55) | GLAL3MBTL1TSHRMAPK1ALDH1A1 | |
| SCHEMBL10880239 | 0.89 | ALDH1A1 (0.56) | GLAL3MBTL1TSHRMAPK1PARP10 | |
| SCHEMBL28192820 | 0.89 | MEN1 (0.50) | GLAL3MBTL1TSHRMAPK1PARP10 | |
| SCHEMBL9410550 | 0.88 | L3MBTL1 (0.47) | GLAL3MBTL1TSHRMAPK1PARP10 | |
| SCHEMBL9636259 | 0.85 | MAPT (0.53) | ALDH1A1LMNAGAAMEN1KMT2A | |
| SCHEMBL28192819 | 0.83 | LMNA (0.48) | GLAL3MBTL1LMNAHCRTR1MEN1 | |
| SCHEMBL27249010 | 0.82 | ALDH1A1 (0.52) | L3MBTL1MAPK1ALDH1A1LMNAGAA | |
| SCHEMBL1672245 | 0.82 | CA12 (0.61) | GLAL3MBTL1TSHRALDH1A1LMNA | |
| SCHEMBL5088087 | 0.82 | CA9 (0.54) | GLAL3MBTL1TSHRALDH1A1LMNA | |
| SCHEMBL9712762 | 0.80 | L3MBTL1 (0.52) | GLAL3MBTL1ALDH1A1HCRTR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015055994-A1 | CYCLOPENTYLBENZAMIDE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF PSYCHOTIC AND COGNITIVE DISORDERS | TAKEDA CAMBRIDGE LIMITED (GB) | 2015-04-23 | — | — | WO | disclosed |