Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 4/20 | 0.57 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.57 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.55 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.55 |
| ▸ | RARB | P10826 | 1/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9453929 | 0.87 | CYSLTR2 (0.61) | S1PR1S1PR2S1PR3ALDH1A1CYSLTR2 | |
| SCHEMBL14544331 | 0.83 | ALDH1A1 (0.46) | S1PR1S1PR2S1PR3ALDH1A1CYSLTR2 | |
| SCHEMBL18910999 | 0.83 | CA2 (0.48) | S1PR1S1PR2S1PR3ALDH1A1HSD17B10 | |
| SCHEMBL11838225 | 0.83 | ALDH1A1 (0.58) | S1PR1S1PR2S1PR3ALDH1A1HSD17B10 | |
| SCHEMBL10482320 | 0.79 | HSD17B10 (0.71) | S1PR1S1PR2S1PR3ALDH1A1HSD17B10 | |
| SCHEMBL1206307 | 0.79 | ALDH1A1 (0.71) | S1PR1S1PR2S1PR3ALDH1A1HSD17B10 | |
| SCHEMBL11828490 | 0.79 | CYSLTR2 (0.63) | S1PR1S1PR2S1PR3ALDH1A1HSD17B10 | |
| SCHEMBL27747821 | 0.79 | ALDH1A1 (0.51) | S1PR1S1PR2S1PR3ALDH1A1HSD17B10 | |
| SCHEMBL8897008 | 0.79 | PTGER2 (0.50) | S1PR1S1PR2S1PR3ALDH1A1HSD17B10 | |
| SCHEMBL30949014 | 0.78 | ESR1 (0.58) | S1PR1S1PR2S1PR3ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251466-A2 | Chemical process for the preparation of esters of substituted cyclopropyl caboxylic acids | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-01-07 | — | — | EP | disclosed |