Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 6/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.47 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 3/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8896340 | 0.89 | PTGER2 (0.43) | PTGER2PTGER4PTGER3PPARGPPARA | |
| SCHEMBL10650968 | 0.88 | PTGER2 (0.63) | PTGER2PTGER4PTGER3PPARGPPARA | |
| SCHEMBL8898411 | 0.88 | CA12 (0.43) | PTGER2PPARGPPARAALDH1A1 | |
| SCHEMBL10651370 | 0.88 | PTGER2 (0.63) | PTGER2PTGER4PTGER3PPARGPPARA | |
| SCHEMBL9453938 | 0.88 | PTGER2 (0.63) | PTGER2PTGER4PTGER3PPARGPPARA | |
| SCHEMBL8895651 | 0.88 | HDAC3 (0.43) | PTGER2PPARGPPARA | |
| SCHEMBL26239913 | 0.85 | ALDH1A1 (0.55) | PLK1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL9233223 | 0.84 | FAAH (0.49) | PTGER2ALDH1A1 | |
| SCHEMBL8421753 | 0.83 | PTGER2 (0.47) | PTGER2PTGER4PTGER3PPARGPPARA | |
| SCHEMBL9235461 | 0.83 | FAAH (0.51) | PTGER2PPARGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5597848-A | PLATELET AGGREGATION INHIBITORS, ANTITHROMBOTIC AGENTS, ANTIASTHMATIC AGENTS, ANTIALLERGIC AGENTS | HOKURIKU SEIYAKU CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0663392-A1 | BENZENESULFONAMIDE DERIVATIVE AND USE THEREOF | HOKURIKU SEIYAKU CO., LTD. (JP) | 1995-07-19 | — | — | EP | disclosed |