Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13626312 | 0.70 | ALDH1A1 (0.41) | ALDH1A1MTNR1AMTNR1BCYP1A2ADRA2A | |
| SCHEMBL14037744 | 0.64 | HDAC9 (0.41) | ALDH1A1MTNR1AMTNR1BCYP1A2ADRA2A | |
| SCHEMBL5970889 | 0.63 | HDAC9 (0.45) | MTNR1AMTNR1BKMT2AHDAC9LMNA | |
| SCHEMBL2464897 | 0.62 | HDAC9 (0.44) | ALDH1A1MTNR1AMTNR1BHDAC9HCAR2 | |
| SCHEMBL14968487 | 0.61 | L3MBTL1 (0.41) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL8457160 | 0.61 | HDAC9 (0.43) | MTNR1AMTNR1BHDAC9LMNAHCAR2 | |
| SCHEMBL8295839 | 0.61 | HDAC9 (0.38) | MTNR1AMTNR1BCYP1A2ADRA2AMAOA | |
| SCHEMBL547428 | 0.61 | MEN1 (0.44) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL20738515 | 0.61 | MME (0.48) | ALDH1A1MTNR1AMTNR1BHDAC9LMNA | |
| SCHEMBL14968650 | 0.61 | NOTUM (0.36) | ALDH1A1HDAC9NOTUMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4783514-A | Polymeric monoarylcyclobutane compositions | THE DOW CHEMICAL COMPANY (US) | 1988-11-08 | — | — | US | disclosed |