Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2464897 | 0.83 | HDAC9 (0.44) | ALDH1A1HDAC9MTNR1AMTNR1B | |
| SCHEMBL21376364 | 0.80 | KDM1A (0.46) | HDAC9 | |
| SCHEMBL14037744 | 0.76 | HDAC9 (0.41) | ALDH1A1HTR2CHTR2BCYP1A2ADRA2A | |
| SCHEMBL2590935 | 0.75 | HTR2A (0.39) | HTR2A | |
| SCHEMBL13626308 | 0.72 | MTNR1A (0.46) | MTNR1AMTNR1BLMNA | |
| SCHEMBL28770234 | 0.71 | SMN1; SMN2 (0.38) | ALDH1A1MAOANOTUMMTNR1AMTNR1B | |
| SCHEMBL10691252 | 0.70 | ALDH1A1 (0.33) | ALDH1A1HTR2CHTR2BCYP1A2ADRA2A | |
| SCHEMBL5970889 | 0.70 | HDAC9 (0.45) | HDAC9MTNR1AMTNR1BLMNAHTT | |
| Bromide SCHEMBL10516381 | 0.70 | MTNR1A (0.36) | ALDH1A1HTR2CHTR2BCYP1A2ADRA2A | |
| SCHEMBL20738653 | 0.69 | HDAC9 (0.41) | HDAC9MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009138440-A1 | CARBAMOYL DERIVATIVES OF BICYCLIC CARBONYLAMINO-PYRAZOLES AS PRODRUGS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2009-11-19 | — | — | WO | disclosed |