Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29228946 | 0.90 | PGR (0.40) | ALDH1A1KDM4ENPC1HPGDMAOB | |
| SCHEMBL7269085 | 0.86 | LMNA (0.40) | ALDH1A1TDP1BLMKDM4EMEN1 | |
| SCHEMBL1832098 | 0.84 | ALDH1A1 (0.44) | ALDH1A1TDP1KDM4EMEN1KMT2A | |
| SCHEMBL30158292 | 0.84 | ALDH1A1 (0.44) | ALDH1A1TDP1KDM4EMEN1KMT2A | |
| SCHEMBL30718143 | 0.82 | MAPT (0.41) | ALDH1A1TDP1KDM4EMEN1KMT2A | |
| SCHEMBL9100845 | 0.82 | MAPT (0.41) | ALDH1A1TDP1KDM4EMEN1KMT2A | |
| SCHEMBL9100407 | 0.77 | LMNA (0.40) | ALDH1A1TDP1BLMKDM4EMEN1 | |
| SCHEMBL9480353 | 0.77 | CYP1A2 (0.41) | ALDH1A1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL1573994 | 0.76 | MEN1 (0.36) | ALDH1A1TDP1BLMKDM4EMEN1 | |
| SCHEMBL10433231 | 0.76 | GSK3A (0.41) | ALDH1A1KDM4EMEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4732991-A | Substituted phthalides | HILTON DAVIS CHEMICAL CO. (US) | 1988-03-22 | — | — | US | disclosed |
| US-4595768-A | 3-(substituted phenyl)phthalides | THE HILTON-DAVIS CHEMICAL CO. (US) | 1986-06-17 | — | — | US | disclosed |