Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 6/20 | 0.48 |
| ▸ | CA2 | P00918 | 10/20 | 0.46 |
| ▸ | CA1 | P00915 | 9/20 | 0.41 |
| ▸ | CA9 | Q16790 | 5/20 | 0.41 |
| ▸ | CA6 | P23280 | 3/20 | 0.41 |
| ▸ | CA5A | P35218 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8060708 | 0.89 | CA2 (0.43) | PTGES2CA2CA1CA9CA6 | |
| SCHEMBL29469931 | 0.84 | PTGES2 (0.55) | PTGES2CA2CA1CA9CA6 | |
| SCHEMBL692280 | 0.84 | PTGES2 (0.55) | PTGES2CA2CA1CA9CA6 | |
| SCHEMBL7865867 | 0.83 | TRPV4 (0.41) | PTGES2CA2TSHRMAPK1SLC22A12 | |
| Hydrochloric Acid SCHEMBL29995248 | 0.82 | PTGES2 (0.53) | PTGES2CA2CA1CA9CA6 | |
| Hydrochloric Acid SCHEMBL4436765 | 0.82 | PTGES2 (0.53) | PTGES2CA2CA1CA9CA6 | |
| SCHEMBL10639576 | 0.81 | CA2 (0.47) | PTGES2CA2CA1CA9CA6 | |
| SCHEMBL11054429 | 0.79 | CA2 (0.46) | PTGES2CA2CA1CA9CA6 | |
| SCHEMBL17595937 | 0.78 | CA2 (0.47) | PTGES2CA2CA1CA9CA6 | |
| SCHEMBL10639175 | 0.78 | CA2 (0.45) | PTGES2CA2CA1CA9CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0064322-B1 | BENZENESULFONYL ISOCYANATES, ISOTHIOCYANATES, CHLORIDES, AND SULFONAMIDES HAVING A FLUORINATED SUBSTITUENT | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-05-22 | — | — | EP | claimed |
| EP-0064322-A2 | Benzenesulfonyl isocyanates, isothiocyanates, chlorides, and sulfonamides having a fluorinated substituent | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-11-10 | — | — | EP | claimed |
| US-4780126-A | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1988-10-25 | — | — | US | disclosed |
| US-4534788-A | CONTROLLING WEEDS IN WHEAT | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-08-13 | — | — | US | disclosed |
| EP-0064322-B1 | BENZENESULFONYL ISOCYANATES, ISOTHIOCYANATES, CHLORIDES, AND SULFONAMIDES HAVING A FLUORINATED SUBSTITUENT | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-05-22 | — | — | EP | disclosed |
| US-4452628-A | TRIAZINYL BENZENE SULFONAMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-06-05 | — | — | US | disclosed |
| EP-0023422-B1 | HERBICIDAL SULFONAMIDES, PREPARATION AND USE THEREOF, AND COMPOSITIONS CONTAINING THEM | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-02-22 | — | — | EP | disclosed |
| EP-0064322-A2 | Benzenesulfonyl isocyanates, isothiocyanates, chlorides, and sulfonamides having a fluorinated substituent | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-11-10 | — | — | EP | disclosed |
| EP-0023422-A2 | Herbicidal sulfonamides, preparation and use thereof, and compositions containing them | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-02-04 | — | — | EP | disclosed |