SCHEMBL8060708

SCHEMBL8060708

NS(=O)(=O)c1ccccc1OC(F)(F)C(F)Cl

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA2 P00918 9/20 0.43
PTGES2 Q9H7Z7 5/20 0.40
LMNA P02545 1/20 0.39
POLB P06746 1/20 0.39
CA1 P00915 8/20 0.38
CA9 Q16790 4/20 0.38
CA6 P23280 3/20 0.38
CA5A P35218 3/20 0.38
CA4 P22748 2/20 0.38
CA12 O43570 2/20 0.38
CA7 P43166 2/20 0.38
CA5B Q9Y2D0 2/20 0.38
CYP2C9 P11712 1/20 0.38
CA14 Q9ULX7 1/20 0.38
CNR2 P34972 1/20 0.35
SLC22A12 Q96S37 2/20 0.35
ELANE P08246 1/20 0.34
CDK2 P24941 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10691561 0.89 PTGES2 (0.48) CA2PTGES2CA1CA9CA6
SCHEMBL692280 0.80 PTGES2 (0.55) CA2PTGES2CA1CA9CA6
SCHEMBL29469931 0.80 PTGES2 (0.55) CA2PTGES2CA1CA9CA6
SCHEMBL7751646 0.79 LMNA (0.42) LMNAPOLB
Hydrochloric Acid SCHEMBL29995248 0.78 PTGES2 (0.53) CA2PTGES2CA1CA9CA6
SCHEMBL27805477 0.78 CA2 (0.41) CA2LMNAPOLBCA1CA5A
Hydrochloric Acid SCHEMBL4436765 0.78 PTGES2 (0.53) CA2PTGES2CA1CA9CA6
SCHEMBL17595937 0.78 CA2 (0.47) CA2PTGES2CA1CA9CA6
SCHEMBL9807509 0.78 CA1 (0.35) CA2PTGES2LMNAPOLBCA1
SCHEMBL10639175 0.78 CA2 (0.45) CA2PTGES2CA1CA9CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0628034-B1 N- (1,3,5-TRIAZINE-2-YL)AMINOCARBONYL]BENZENE SULPHONAMIDE HERBICIDES BASF AG (DE) 2000-12-20 EP disclosed
US-5488029-A Herbicidal N- [1,3,5-riazin-2-yl)-aminocarbonyl]-benzenesulfonamides BASF AKTIENGESELLSCHAFT (DE) 1996-01-30 US disclosed
EP-0628034-A1 N- (1,3,5-TRIAZINE-2-YL)AMINOCARBONYL]BENZENE SULPHONAMIDE HERBICIDES BASF Aktiengesellschaft (DE) 1994-12-14 EP disclosed
WO-1993017001-A1 N-[(1,3,5-TRIAZINE-2-YL)AMINOCARBONYL]BENZENE SULPHONAMIDE HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1993-09-02 WO disclosed