Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 10/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GRK6 | P43250 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7778136 | 0.91 | ALDH1A1 (0.44) | ALDH1A1TSHRCNR2MEN1KMT2A | |
| SCHEMBL10999527 | 0.90 | ALDH1A1 (0.43) | ALDH1A1TSHRCNR2MEN1KMT2A | |
| SCHEMBL10689753 | 0.90 | ALDH1A1 (0.42) | ALDH1A1TSHRCNR2MEN1KMT2A | |
| SCHEMBL7778133 | 0.88 | ALDH1A1 (0.43) | ALDH1A1TSHRCNR2MEN1KMT2A | |
| SCHEMBL8324518 | 0.86 | L3MBTL1 (0.44) | ALDH1A1TSHRCNR2MEN1KMT2A | |
| SCHEMBL10687283 | 0.85 | SMN1; SMN2 (0.39) | ALDH1A1TSHRCNR2MEN1KMT2A | |
| SCHEMBL7778164 | 0.85 | ALDH1A1 (0.48) | ALDH1A1TSHRCNR2MEN1KMT2A | |
| SCHEMBL10692670 | 0.83 | SLC2A1 (0.50) | ALDH1A1TSHRMEN1KMT2AL3MBTL1 | |
| SCHEMBL10689098 | 0.82 | TDP1 (0.39) | ALDH1A1TSHRMEN1KMT2AL3MBTL1 | |
| SCHEMBL7778519 | 0.81 | CNR2 (0.43) | ALDH1A1TSHRCNR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4732991-A | Substituted phthalides | HILTON DAVIS CHEMICAL CO. (US) | 1988-03-22 | — | — | US | disclosed |
| US-4595768-A | 3-(substituted phenyl)phthalides | THE HILTON-DAVIS CHEMICAL CO. (US) | 1986-06-17 | — | — | US | disclosed |